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UGID:158634     UniGene Hs.175955     Homo sapiens (human)   YTHDC1
YTH domain containing 1 (YTHDC1)

Human protein-coding gene YTHDC1. Represented by 475 ESTs from 238 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 158634 - Hs.175955]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_517262.2 PREDICTED: YTH domain-containing protein 1 isoform 2 P. troglodytes 100.0 726
NP_001026902.1 YTHDC1 gene product H. sapiens 100.0 726
XP_001098270.2 PREDICTED: YTH domain-containing protein 1-like isoform 1 M. mulatta 99.9 727
XP_003898878.1 PREDICTED: YTH domain-containing protein 1 isoform 1 P. anubis 99.9 727
NP_808348.2 YTH domain containing 1 M. musculus 98.6 735
NP_001088293.1 YTH domain containing 1 X. laevis 86.6 701
NP_001007411.1 ythdc1 gene product D. rerio 81.2 678
NP_728876.1 YT521-B, isoform B D. melanogaster 58.2 244
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
XP_001501576.1 PREDICTED: YTH domain-containing protein 1 isoform 2 E. caballus 98.9 729
XP_004009917.1 PREDICTED: YTH domain-containing protein 1 O. aries 98.9 727

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uterus; kidney; testis; mixed; liver; heart; mammary gland; placenta; uncharacterized tissue; adipose tissue; intestine; eye; pancreas; embryonic tissue; lung; mouth; prostate; thymus; blood; vascular; stomach; skin; pituitary gland; spleen; esophagus; trachea; connective tissue; amniotic fluid; adrenal gland; lymph node; pharynx; bladder; salivary gland; lymph; muscle; nerve; bone; thyroid; ovary; bone marrow; larynx; cervix; parathyroid
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q13.2
UniSTS entry: Chr 4 SHGC-24716 [Map Viewer]
UniSTS entry: Chr 4 YTHDC1
UniSTS entry: Chr 4 RH91859
UniSTS entry: Chr 4 RH91333
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AL049340.1 Homo sapiens mRNA; cDNA DKFZp564P056 (from clone DKFZp564P056) A
BC053863.1 Homo sapiens YTH domain containing 1, mRNA (cDNA clone MGC:61557 IMAGE:4933750), complete cds PA
BC041119.1 Homo sapiens YTH domain containing 1, mRNA (cDNA clone MGC:47781 IMAGE:5541053), complete cds PA
NM_001031732.2 Homo sapiens YTH domain containing 1 (YTHDC1), transcript variant 1, mRNA P
AK056430.1 Homo sapiens cDNA FLJ31868 fis, clone NT2RP7001962, highly similar to Rattus norvegicus YT521 mRNA for RNA splicing-related protein P
AB075846.1 Homo sapiens mRNA for KIAA1966 protein P
NM_133370.2 Homo sapiens YTH domain containing 1 (YTHDC1), transcript variant 2, mRNA P
AK098515.1 Homo sapiens cDNA FLJ25649 fis, clone SYN01041, highly similar to Rattus norvegicus YT521 mRNA for RNA splicing-related protein P
AK090836.1 Homo sapiens cDNA FLJ33517 fis, clone BRAMY2005708
AL832559.1 Homo sapiens mRNA; cDNA DKFZp547E1518 (from clone DKFZp547E1518) PA
AL157447.1 Homo sapiens mRNA; cDNA DKFZp761C1811 (from clone DKFZp761C1811) A

EST sequences (10 of 475) [Show all sequences]

R14060.1 Clone IMAGE:27115 brain 5' read
AA969681.1 Clone IMAGE:1579211 mixed 3' read A
AA983531.1 Clone IMAGE:1553698 kidney 3' read A
AA905026.1 Clone IMAGE:1507312 mixed 3' read A
AI018040.1 Clone IMAGE:1642086 testis 3' read A
R18383.1 Clone IMAGE:30828 brain 5' read P
AI051913.1 Clone IMAGE:1649063 parathyroid 3' read A
AI082831.1 Clone IMAGE:1662434 mixed 3' read
CB045447.1 Clone IMAGE:3218377 intestine 3' read A
CB051011.1 Clone IMAGE:3289472 prostate 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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