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UGID:158438     UniGene Hs.174030     Homo sapiens (human)   ADAM28
ADAM metallopeptidase domain 28 (ADAM28)

Human protein-coding gene ADAM28. Represented by 77 ESTs from 54 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 158438 - Hs.174030]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055080.2 ADAM28 gene product H. sapiens 100.0 774
NP_001041640.1 Adam28 gene product M. musculus 75.1 768
NP_001121218.1 ADAM metallopeptidase domain 7 precursor X. laevis 55.4 327
Other hits (2 of 22) [Show all]SpeciesId(%)Len(aa)
XP_519663.3 PREDICTED: disintegrin and metalloproteinase domain-containing protein 28 isoform 2 P. troglodytes 98.5 540
XP_001106707.1 PREDICTED: disintegrin and metalloproteinase domain-containing protein 28-like M. mulatta 94.7 775

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: ovary; stomach; uncharacterized tissue; mixed; kidney; thyroid; placenta; mammary gland; brain; pancreas; muscle; uterus; spleen; blood; connective tissue; thymus; testis; mouth; trachea; larynx; lymph; lung; lymph node; intestine; embryonic tissue; bladder
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p21.2
UniSTS entry: Chr 8 RH79000 [Map Viewer]
UniSTS entry: Chr 1 D11S3114
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AJ242015.1 Homo sapiens mRNA for eMDC II protein PA
NM_014265.4 Homo sapiens ADAM metallopeptidase domain 28 (ADAM28), transcript variant 1, mRNA P
AF137334.1 Homo sapiens metalloprotease disintegrin cysteine-rich protein, transmembrane form mRNA, complete cds PA
AF137335.1 Homo sapiens metalloprotease disintegrin cysteine-rich protein, secreted form mRNA, complete cds PA
NM_021777.3 Homo sapiens ADAM metallopeptidase domain 28 (ADAM28), transcript variant 3, mRNA P
AK225921.1 Homo sapiens mRNA for ADAM metallopeptidase domain 28 isoform 1 preproprotein variant, clone: FCC118C07 PA
BC136478.1 Homo sapiens ADAM metallopeptidase domain 28, mRNA (cDNA clone MGC:168090 IMAGE:9020467), complete cds P
AK293382.1 Homo sapiens cDNA FLJ60418 complete cds, highly similar to ADAM 28 precursor (EC 3.4.24.-) (Adisintegrin and metalloproteinase domain 28) P
AK303437.1 Homo sapiens cDNA FLJ61514 complete cds, highly similar to ADAM 28 precursor (EC 3.4.24.-) (Adisintegrin and metalloproteinase domain 28) P
BC144140.1 Homo sapiens cDNA clone IMAGE:9052660, containing frame-shift errors P

EST sequences (10 of 77) [Show all sequences]

AI301513.1 Clone IMAGE:1901145 kidney 3' read A
AI364737.1 Clone IMAGE:2020842 uncharacterized tissue 3' read
AI393447.1 Clone IMAGE:2111723 mixed 3' read
AI475787.1 Clone IMAGE:2073801 uncharacterized tissue 3' read A
AI470208.1 Clone IMAGE:2148948 mixed 3' read A
AI499503.1 Clone IMAGE:2177868 uterus 3' read
AI624420.1 Clone IMAGE:2230014 pancreas 3' read
AI624552.1 Clone IMAGE:2230080 pancreas 3' read A
AI696897.1 Clone IMAGE:2324457 pancreas 3' read
AI709066.1 Clone IMAGE:2335598 intestine 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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