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UGID:158073     UniGene Hs.171501     Homo sapiens (human)   USP11
Ubiquitin specific peptidase 11 (USP11)

Human protein-coding gene USP11. Represented by 2900 ESTs from 406 cDNA libraries. Corresponds to reference sequence NM_004651.3. [UniGene 158073 - Hs.171501]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_004642.2 USP11 gene product H. sapiens 100.0 962
XP_003917678.1 PREDICTED: LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 11 P. anubis 99.9 962
XP_001093504.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase 11 isoform 4 M. mulatta 99.8 962
XP_003954471.1 PREDICTED: LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 11, partial P. troglodytes 99.6 786
NP_663603.3 Usp11 gene product M. musculus 89.6 920
XP_002662557.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase 4 isoform 2 D. rerio 61.0 908
NP_001082452.1 ubiquitin specific peptidase 4 (proto-oncogene) X. laevis 60.6 933
NP_174562.2 ubiquitin carboxyl-terminal hydrolase 4/11/15 A. thaliana 57.0 586
XP_001702430.1 predicted protein C. reinhardtii 55.0 346
NP_501035.1 Protein H34C03.2 C. elegans 52.2 591
NP_649153.1 CG8334, isoform A D. melanogaster 50.9 285
XP_956165.2 hypothetical protein NCU00480 N. crassa 50.3 820
NP_012338.1 Ubp12p S. cerevisiae 50.0 216
Other hits (2 of 57) [Show all]SpeciesId(%)Len(aa)
NP_001183969.1 USP11 gene product C. lupus familiaris 93.9 765
NP_001073777.1 USP11 gene product B. taurus 92.8 751

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; lung; thymus; uterus; pancreas; uncharacterized tissue; kidney; embryonic tissue; eye; intestine; skin; spleen; mouth; liver; mammary gland; placenta; prostate; pharynx; bladder; bone marrow; trachea; ovary; lymph; cervix; muscle; blood; stomach; mixed; lymph node; connective tissue; thyroid; pituitary gland; vascular; ascites; nerve; bone; ganglia; pineal gland; heart; adrenal gland; umbilical cord; salivary gland; ear; tonsil; esophagus; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xp11.23
UniSTS entry: Chr X DXS1180E
UniSTS entry: Chr X WIAF-2542
UniSTS entry: Chr X RH35861
UniSTS entry: DXS1180E
UniSTS entry: Chr X DXS7590
UniSTS entry: Chr X DXS7590
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_004651.3 Homo sapiens ubiquitin specific peptidase 11 (USP11), mRNA PA
BC063668.1 Homo sapiens ubiquitin specific peptidase 11, mRNA (cDNA clone IMAGE:4180680), partial cds PA
BC000350.2 Homo sapiens ubiquitin specific peptidase 11, mRNA (cDNA clone IMAGE:2961383), partial cds PA
U44839.1 Human putative ubiquitin C-terminal hydrolase (UHX1) mRNA, complete cds PA
BC140849.1 Homo sapiens ubiquitin specific peptidase 11, mRNA (cDNA clone MGC:176526 IMAGE:9021717), complete cds P
AK098394.1 Homo sapiens cDNA FLJ25528 fis, clone CBR07442, highly similar to UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 11 (EC 3.1.2.15) P
AK294635.1 Homo sapiens cDNA FLJ61237 complete cds, highly similar to Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) P
AB073597.1 Homo sapiens usp11 mRNA for deubiquitinating enzyme, complete cds P

EST sequences (10 of 2900) [Show all sequences]

T05538.1 Clone HFBDC07 brain
AA984681.1 Clone IMAGE:1630227 brain 3' read P
AA993732.1 Clone IMAGE:1620010 testis 3' read P
AI015738.1 Clone IMAGE:1622226 embryonic tissue 3' read P
T06015.1 Clone HFBDM07 brain
AI074496.1 Clone IMAGE:1670118 brain 3' read
AI076454.1 Clone IMAGE:1675587 mixed 3' read P
R23512.1 Clone IMAGE:33905 brain 5' read P
R23520.1 Clone IMAGE:34118 brain 5' read P
AI143169.1 Clone IMAGE:1708753 heart 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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