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UGID:157252     UniGene Hs.167679     Homo sapiens (human)   SH3BP2
SH3-domain binding protein 2 (SH3BP2)

Human protein-coding gene SH3BP2. Represented by 333 ESTs from 187 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 157252 - Hs.167679]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001139328.1 SH3BP2 gene product H. sapiens 100.0 617
NP_001139331.1 SH3 domain-binding protein 2 isoform b M. musculus 93.2 614
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_003890928.1 PREDICTED: SH3 domain-binding protein 2 isoform 3 P. anubis 97.7 617
XP_001088909.2 PREDICTED: SH3 domain-binding protein 2 M. mulatta 97.2 617

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; uncharacterized tissue; mixed; blood; kidney; spleen; placenta; mouth; cervix; mammary gland; intestine; uterus; liver; testis; ganglia; pharynx; connective tissue; bone; bladder; lymph; tonsil; adrenal gland; lymph node; eye; vascular; thymus; bone marrow; embryonic tissue; thyroid; skin; nerve; muscle; prostate; salivary gland; ovary; stomach; larynx; heart
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4p16.3
UniSTS entry: Chr 4 SHGC-68227 [Map Viewer]
UniSTS entry: Chr 4 STS-H16766 [Map Viewer]
UniSTS entry: Chr 4 RH68130 [Map Viewer]
UniSTS entry: Chr 4 D4S3283 [Map Viewer]
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 1 L17971
UniSTS entry: Chr 1 GDB:434012
UniSTS entry: Chr 1 L30021
UniSTS entry: Chr 4 SH3BP2__6823
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

AK124073.1 Homo sapiens cDNA FLJ42079 fis, clone SYNOV2021320, highly similar to SH3 DOMAIN-BINDING PROTEIN 3BP-2 P
NM_003023.4 Homo sapiens SH3-domain binding protein 2 (SH3BP2), transcript variant 1, mRNA P
AK225497.1 Homo sapiens mRNA for SH3 domain-binding protein 2 variant, clone: JTH09395 PA
AK307106.1 Homo sapiens cDNA, FLJ97054 P
AK312286.1 Homo sapiens cDNA, FLJ92588, highly similar to Homo sapiens SH3-domain binding protein 2 (SH3BP2), mRNA P
BC022996.1 Homo sapiens SH3-domain binding protein 2, mRNA (cDNA clone MGC:29882 IMAGE:5103986), complete cds PA
NM_001122681.1 Homo sapiens SH3-domain binding protein 2 (SH3BP2), transcript variant 2, mRNA P
AK299996.1 Homo sapiens cDNA FLJ55522 complete cds, highly similar to SH3 domain-binding protein 2 PA
NM_001145856.1 Homo sapiens SH3-domain binding protein 2 (SH3BP2), transcript variant 3, mRNA P
NM_001145855.1 Homo sapiens SH3-domain binding protein 2 (SH3BP2), transcript variant 4, mRNA P
L37198.1 Homo sapiens (clone B3B3E13) Huntington's disease candidate region mRNA fragment
AB000462.1 Homo sapiens mRNA for SH3 binding protein, complete cds, clone:RES4-23A P
AF000936.1 Homo sapiens SH3 binding protein 2 mRNA, complete cds P
U56386.1 Human SH3 binding protein 3BP2 (3BP2) mRNA, complete cds P

EST sequences (10 of 333) [Show all sequences]

AA910863.1 Clone IMAGE:1520746 kidney 3' read
AI080398.1 Clone IMAGE:1662737 mixed 3' read A
AI088383.1 Clone IMAGE:1695921 uterus 3' read A
AI093427.1 Clone IMAGE:1695630 uterus 3' read A
AI140758.1 Clone IMAGE:1690205 mixed 3' read A
CB054178.1 Clone IMAGE:3291485 brain 5' read
BX109041.1 Clone IMAGp998C08282_;_IMAGE:50122 brain A
AI286324.1 Clone IMAGE:1979496 stomach 3' read A
R48131.1 Clone IMAGE:153694 mammary gland 5' read
R48132.1 Clone IMAGE:153694 mammary gland 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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