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UGID:156679     UniGene Hs.163846     Homo sapiens (human)   N6AMT1
N-6 adenine-specific DNA methyltransferase 1 (putative) (N6AMT1)

Human protein-coding gene N6AMT1. Represented by 51 ESTs from 38 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 156679 - Hs.163846]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_037372.3 N6AMT1 gene product H. sapiens 100.0 213
NP_080642.1 N6-DNA methyltransferase A isoform 1 M. musculus 91.1 213
NP_001089552.1 N-6 adenine-specific DNA methyltransferase 1 (putative) X. laevis 75.8 207
NP_001002502.1 n6amt1 gene product D. rerio 66.0 212
NP_494209.2 Protein C33C12.9 C. elegans 50.0 198
XP_001690107.1 N6-DNA-methyltransferase C. reinhardtii 46.5 200
Other hits (2 of 33) [Show all]SpeciesId(%)Len(aa)
XP_001103046.1 PREDICTED: N(6)-adenine-specific DNA methyltransferase 1 isoform 1 M. mulatta 98.6 213
XP_525443.2 PREDICTED: hemK methyltransferase family member 2 isoform 2 P. troglodytes 98.6 213

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; pancreas; uterus; kidney; mixed; blood; liver; embryonic tissue; placenta; uncharacterized tissue; ovary; testis; heart; skin; vascular; muscle; spleen; lymph node; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 21
Map position: 21q21.3
UniSTS entry: Chr 21 RH93987
UniSTS entry: Chr 21 RH80363
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_182749.3 Homo sapiens N-6 adenine-specific DNA methyltransferase 1 (putative) (N6AMT1), transcript variant 2, mRNA PA
NM_013240.4 Homo sapiens N-6 adenine-specific DNA methyltransferase 1 (putative) (N6AMT1), transcript variant 1, mRNA PA
AF139682.1 Homo sapiens putative N5-methyl-Gln methyltransferase mRNA, complete cds PA
AK021678.1 Homo sapiens cDNA FLJ11616 fis, clone HEMBA1004038
AK225515.1 Homo sapiens mRNA for N6-DNA-methyltransferase isoform 1 variant, clone: KAT06375 PA
BC011554.1 Homo sapiens N-6 adenine-specific DNA methyltransferase 1 (putative), mRNA (cDNA clone MGC:19995 IMAGE:4640080), complete cds PA
AK314100.1 Homo sapiens cDNA, FLJ94785, Homo sapiens putative N6-DNA-methyltransferase (N6AMT1), mRNA P
NR_047510.1 Homo sapiens N-6 adenine-specific DNA methyltransferase 1 (putative) (N6AMT1), transcript variant 3, non-coding RNA PA

EST sequences (10 of 51) [Show all sequences]

AI311671.1 Clone IMAGE:1915889 kidney 3' read
AI421382.1 Clone IMAGE:2096758 brain 3' read PA
AI523341.1 Clone IMAGE:2128746 vascular 3' read
AU280589.1 Clone N1ESE2002690 uncharacterized tissue 5' read P
BX281239.1 Clone IMAGp998D1611405_;_IMAGE:5163231 brain P
CD109976.1 Clone IMAGE:30346675 placenta 5' read P
BX338874.2 Clone CS0DI065YA09 placenta 5' read
BX344282.2 Clone CS0DI075YA21 placenta 5' read P
BX391862.2 Clone CS0DJ001YK09 blood 3' read
BX503182.1 Clone DKFZp779F1872 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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