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UGID:156637     UniGene Hs.163555     Homo sapiens (human)   PANK1
Pantothenate kinase 1 (PANK1)

Human protein-coding gene PANK1. Represented by 99 ESTs from 66 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 156637 - Hs.163555]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_683878.1 PANK1 gene product H. sapiens 100.0 597
XP_001143095.1 PREDICTED: pantothenate kinase 1 isoform 3 P. troglodytes 99.7 597
NP_001107811.1 Pank1 gene product M. musculus 95.2 544
NP_001077310.1 pank1b gene product D. rerio 88.9 432
NP_001086598.1 pantothenate kinase 3 X. laevis 80.1 367
NP_001246848.1 fumble, isoform G D. melanogaster 69.8 377
NP_176247.2 Pantothenate kinase 1 A. thaliana 50.0 182
NP_010820.3 pantothenate kinase S. cerevisiae 45.6 206
Other hits (2 of 39) [Show all]SpeciesId(%)Len(aa)
XP_003904030.1 PREDICTED: pantothenate kinase 1 P. anubis 99.3 597
XP_848922.1 PREDICTED: pantothenate kinase 1 isoform 1 C. lupus familiaris 99.2 372

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; cervix; pancreas; lymph node; eye; bladder; muscle; mixed; uncharacterized tissue; uterus; embryonic tissue; kidney; testis; prostate; mouth; thymus; larynx; liver; stomach; intestine; skin; bone; salivary gland; heart
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q23.31
UniSTS entry: Chr 10 A005K48 [Map Viewer]
UniSTS entry: Chr 10 G20295
UniSTS entry: Chr 10 STS-F09841 [Map Viewer]
UniSTS entry: Chr 10 RH78326 [Map Viewer]
UniSTS entry: Chr 10 SHGC-132396
UniSTS entry: Chr 10 SHGC-2617
UniSTS entry: Chr 1 D11S3114
UniSTS entry: Chr 10 PANK1__5821
UniSTS entry: RH45334
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AY027663.1 Homo sapiens pantothenate kinase 1 gamma (PANK1) mRNA, complete cds, alternatively spliced PA
AY027662.1 Homo sapiens pantothenate kinase 1 beta (PANK1) mRNA, complete cds, alternatively spliced PA
AY027661.1 Homo sapiens pantothenate kinase 1 alpha (PANK1) mRNA, complete cds, alternatively spliced PA
AK127777.1 Homo sapiens cDNA FLJ45878 fis, clone OCBBF3009244, highly similar to Pantothenate kinase 1 (EC 2.7.1.33) P
AK125428.1 Homo sapiens cDNA FLJ43439 fis, clone OCBBF2030354, highly similar to Pantothenate kinase 1 (EC 2.7.1.33) P
AK057932.1 Homo sapiens cDNA FLJ25203 fis, clone REC05438
NM_138316.3 Homo sapiens pantothenate kinase 1 (PANK1), transcript variant gamma, mRNA PA
BC026296.1 Homo sapiens pantothenate kinase 1, mRNA (cDNA clone IMAGE:4244591), complete cds PA
AF355198.1 Homo sapiens pantothenate kinase mRNA, complete cds P
NM_148978.2 Homo sapiens pantothenate kinase 1 (PANK1), transcript variant beta, mRNA PA
NM_148977.2 Homo sapiens pantothenate kinase 1 (PANK1), transcript variant alpha, mRNA PA
BC036934.1 Homo sapiens pantothenate kinase 1, mRNA (cDNA clone IMAGE:5242770), with apparent retained intron PA

EST sequences (10 of 99) [Show all sequences]

R17255.1 Clone IMAGE:31858 brain 5' read
AI002258.1 Clone IMAGE:1601409 lung 3' read A
AI017826.1 Clone IMAGE:1636003 kidney 3' read A
BX096503.1 Clone IMAGp998H16278_;_IMAGE:48659 brain A
BX111959.1 Clone IMAGp998O14152_;_IMAGE:31858 brain A
CB113432.1 Clone B1T694954-1-G10 brain 5' read P
AI274645.1 Clone IMAGE:1986435 uterus 3' read A
AI373299.1 Clone IMAGE:2030175 kidney 3' read A
AI539297.1 Clone IMAGE:2090180 mixed 3' read A
AI401347.1 Clone IMAGE:2113578 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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