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UGID:156354     UniGene Hs.162458     Homo sapiens (human)   PIAS1
Protein inhibitor of activated STAT, 1 (PIAS1)

Human protein-coding gene PIAS1. Represented by 385 ESTs from 196 cDNA libraries. Corresponds to reference sequence NM_016166.1. [UniGene 156354 - Hs.162458]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003901156.1 PREDICTED: E3 SUMO-protein ligase PIAS1 isoform 2 P. anubis 100.0 652
XP_001082929.2 PREDICTED: e3 SUMO-protein ligase PIAS1 isoform 4 M. mulatta 100.0 650
XP_523109.3 PREDICTED: e3 SUMO-protein ligase PIAS1 isoform 2 P. troglodytes 100.0 650
NP_057250.1 PIAS1 gene product H. sapiens 100.0 650
XP_535524.2 PREDICTED: E3 SUMO-protein ligase PIAS1 isoform 1 C. lupus familiaris 100.0 650
XP_003121797.2 PREDICTED: LOW QUALITY PROTEIN: E3 SUMO-protein ligase PIAS1 S. scrofa 99.8 650
NP_001068864.1 PIAS1 gene product B. taurus 99.8 650
XP_001496490.2 PREDICTED: e3 SUMO-protein ligase PIAS1 E. caballus 99.8 641
XP_004010310.1 PREDICTED: E3 SUMO-protein ligase PIAS1 O. aries 99.8 641
XP_002718125.1 PREDICTED: protein inhibitor of activated STAT, 1 O. cuniculus 99.7 641
NP_062637.2 Pias1 gene product M. musculus 99.2 650
NP_001079161.1 protein inhibitor of activated STAT, 1 X. laevis 92.1 648
XP_688159.2 PREDICTED: e3 SUMO-protein ligase PIAS1 isoform 1 D. rerio 88.3 658
NP_724756.1 suppressor of variegation 2-10, isoform E D. melanogaster 56.8 488
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
NP_001100299.2 Pias1 gene product R. norvegicus 99.2 650
XP_001376592.2 PREDICTED: e3 SUMO-protein ligase PIAS1 M. domestica 99.1 641

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; pituitary gland; adipose tissue; mixed; blood; adrenal gland; uterus; pancreas; lung; mammary gland; lymph; larynx; skin; stomach; placenta; prostate; ovary; kidney; liver; embryonic tissue; eye; connective tissue; spleen; heart; pharynx; bladder; vascular; thymus; intestine; trachea; lymph node; mouth; bone marrow; thyroid; ascites; nerve; ganglia; bone; ear; esophagus; pineal gland; muscle; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q
UniSTS entry: Chr 15 D15S1092 [Map Viewer]
UniSTS entry: Chr 1 D1S1425
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AF077951.1 Homo sapiens protein inhibitor of activated STAT protein PIAS1 mRNA, complete cds P
BC053685.1 Homo sapiens protein inhibitor of activated STAT, 1, mRNA (cDNA clone IMAGE:4522230) P
AK128379.1 Homo sapiens cDNA FLJ46522 fis, clone THYMU3034078, highly similar to Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1 P
NM_016166.1 Homo sapiens protein inhibitor of activated STAT, 1 (PIAS1), mRNA PA
AF167160.1 Homo sapiens protein inhibitor of activated STAT-1 (PIAS1) mRNA, complete cds PA
BC104646.1 Homo sapiens protein inhibitor of activated STAT, 1, mRNA (cDNA clone IMAGE:6102271) PA
AY826819.1 Homo sapiens cell proliferation-inducing protein 23 mRNA, complete cds PA
BC118587.1 Homo sapiens protein inhibitor of activated STAT, 1, mRNA (cDNA clone MGC:141879 IMAGE:40085010), complete cds P
BC121797.1 Homo sapiens protein inhibitor of activated STAT, 1, mRNA (cDNA clone MGC:141878 IMAGE:40085007), complete cds P
EF487998.1 Homo sapiens cell-line MB231 protein inhibitor of activated STAT1 (PIAS1) mRNA, complete cds P
EF487997.1 Homo sapiens cell-line HL-60 protein inhibitor of activated STAT1 (PIAS1) mRNA, complete cds P
AK314515.1 Homo sapiens cDNA, FLJ95334, Homo sapiens protein inhibitor of activated STAT, 1 (PIAS1), mRNA P
AK094641.1 Homo sapiens cDNA FLJ37322 fis, clone BRAMY2018126, highly similar to Protein inhibitor of activated STAT protein 1 P
FJ997900.1 Homo sapiens protein inhibitor of activated STAT 1 (PIAS1) mRNA, complete cds, alternatively spliced P
U78524.1 Human Gu binding protein mRNA, partial cds P

EST sequences (10 of 385) [Show all sequences]

AA954320.1 Clone IMAGE:1563032 mixed 3' read A
AA969155.1 Clone IMAGE:1580282 mixed 3' read
AI040228.1 Clone IMAGE:1660340 mixed 3' read PA
R20392.1 Clone IMAGE:32565 brain 5' read P
T06215.1 Clone HFBDQ46 brain P
BX098741.1 Clone IMAGp998F19676_;_IMAGE:301842 lung P
AI253081.1 Clone IMAGE:2029093 kidney 3' read PA
AI263225.1 Clone IMAGE:2029012 kidney 3' read A
CB133735.1 Clone L4SNU368s1-22-H11 liver 5' read P
CB138566.1 Clone L4SNU368s1-17-B07 liver 5' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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