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UGID:155279     UniGene Hs.158322     Homo sapiens (human)   SLC18A1
Solute carrier family 18 (vesicular monoamine), member 1 (SLC18A1)

Human protein-coding gene SLC18A1. Represented by 43 ESTs from 14 cDNA libraries. EST representation biased toward nerve; primitive neuroectodermal tumor of the CNS; juvenile. Corresponds to 4 reference sequences (different isoforms). [UniGene 155279 - Hs.158322]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001129163.1 SLC18A1 gene product H. sapiens 100.0 524
NP_694694.1 Slc18a1 gene product M. musculus 85.6 520
XP_002663262.2 PREDICTED: chromaffin granule amine transporter-like D. rerio 74.7 493
NP_001079414.1 solute carrier family 18 (vesicular monoamine), member 1 X. laevis 59.4 463
NP_001014524.1 vesicular monoamine transporter, isoform C D. melanogaster 58.4 457
NP_001024936.1 Protein CAT-1, isoform a C. elegans 51.7 516
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_001150127.1 PREDICTED: chromaffin granule amine transporter isoform 4 P. troglodytes 98.7 524
XP_003902534.1 PREDICTED: chromaffin granule amine transporter isoform 1 P. anubis 97.0 524

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: nerve [show more like this]
primitive neuroectodermal tumor of the CNS [show more like this]
juvenile [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; brain; testis; spleen; prostate; nerve; mixed; placenta; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p21.3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_003053.3 Homo sapiens solute carrier family 18 (vesicular monoamine), member 1 (SLC18A1), transcript variant 2, mRNA PA
BC006317.2 Homo sapiens solute carrier family 18 (vesicular monoamine), member 1, mRNA (cDNA clone MGC:12717 IMAGE:4125784), complete cds PA
U39905.1 Human vesicular monoamine transporter VMAT1 mRNA, complete cds P
AK313720.1 Homo sapiens cDNA, FLJ94316, highly similar to Homo sapiens solute carrier family 18 (vesicular monoamine), member 1 (SLC18A1), mRNA P
NM_001135691.2 Homo sapiens solute carrier family 18 (vesicular monoamine), member 1 (SLC18A1), transcript variant 1, mRNA PA
NM_001142325.1 Homo sapiens solute carrier family 18 (vesicular monoamine), member 1 (SLC18A1), transcript variant 4, mRNA PA
NM_001142324.1 Homo sapiens solute carrier family 18 (vesicular monoamine), member 1 (SLC18A1), transcript variant 3, mRNA PA

EST sequences (10 of 43) [Show all sequences]

BX283515.1 Clone IMAGp958H151019_;_IMAGE:4127678 brain P
BX376807.2 Clone CS0DD006YE15 uncharacterized tissue 3' read P
BX376808.2 Clone CS0DD006YE15 uncharacterized tissue 5' read P
BX332142.2 Clone CS0DC008YC10 uncharacterized tissue 3' read P
BX332143.2 Clone CS0DC008YC10 uncharacterized tissue 5' read P
BX332580.2 Clone CS0DC013YL17 uncharacterized tissue 3' read P
BX353973.2 Clone CS0DC013YL17 uncharacterized tissue 5' read P
BX353150.2 Clone CS0DC001YE04 uncharacterized tissue 3' read P
BX353151.2 Clone CS0DC001YE04 uncharacterized tissue 5' read P
BX375142.2 Clone CS0DC008YL10 uncharacterized tissue 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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