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UGID:133473     UniGene Hs.15744     Homo sapiens (human)   SH2B1
SH2B adaptor protein 1 (SH2B1)

Human protein-coding gene SH2B1. Represented by 398 ESTs from 196 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 133473 - Hs.15744]

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; intestine; pituitary gland; muscle; uncharacterized tissue; uterus; skin; liver; stomach; eye; nerve; spleen; cervix; lung; lymph node; connective tissue; pancreas; thyroid; embryonic tissue; placenta; mammary gland; thymus; mixed; prostate; kidney; heart; trachea; tonsil; salivary gland; larynx; ascites; bone marrow; bone; ovary; mouth; blood; adrenal gland; vascular
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p11.2
UniSTS entry: Chr 16 SHGC-61052
UniSTS entry: Chr 16 SH2B_9440
UniSTS entry: Chr 1 D1S1425
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

AL049924.1 Homo sapiens mRNA; cDNA DKFZp564G1182 (from clone DKFZp564G1182); partial cds PA
AB037720.1 Homo sapiens mRNA for KIAA1299 protein, partial cds P
AF227967.1 Homo sapiens SH2-B alpha signaling protein (SH2B) mRNA, complete cds, alternatively spliced PA
AF227968.1 Homo sapiens SH2-B beta signaling protein (SH2B) mRNA, complete cds, alternatively spliced PA
AF227969.1 Homo sapiens SH2-B gamma signaling protein (SH2B) mRNA, complete cds, alternatively spliced PA
AK027488.1 Homo sapiens cDNA FLJ14582 fis, clone NT2RM4001411, highly similar to Mus musculus Pro-rich, PH, SH2 domain-containing signaling mediator (PSM) mRNA P
BC010704.1 Homo sapiens SH2B adaptor protein 1, mRNA (cDNA clone MGC:16976 IMAGE:3866324), complete cds PA
AK055104.1 Homo sapiens cDNA FLJ30542 fis, clone BRAWH2001378, highly similar to Rattus norvegicus SH2-B PH domain containing signaling mediator 1 (Sh2bpsm1), transcript variant 1, mRNA P
AK290332.1 Homo sapiens cDNA FLJ75160 complete cds, highly similar to Homo sapiens SH2-B homolog (SH2B), mRNA P
AL713760.1 Homo sapiens mRNA; cDNA DKFZp727I201 (from clone DKFZp727I201) PA
AK298569.1 Homo sapiens cDNA FLJ59376 complete cds, highly similar to Mus musculus SH2B adaptor protein 1 (Sh2b1), mRNA P
AK297080.1 Homo sapiens cDNA FLJ59336 complete cds, highly similar to Homo sapiens SH2-B homolog (SH2B), mRNA P
NM_001145797.1 Homo sapiens SH2B adaptor protein 1 (SH2B1), transcript variant 5, mRNA PA
NM_001145796.1 Homo sapiens SH2B adaptor protein 1 (SH2B1), transcript variant 4, mRNA PA
NM_001145795.1 Homo sapiens SH2B adaptor protein 1 (SH2B1), transcript variant 1, mRNA PA
NM_001145812.1 Homo sapiens SH2B adaptor protein 1 (SH2B1), transcript variant 3, mRNA PA
NM_015503.2 Homo sapiens SH2B adaptor protein 1 (SH2B1), transcript variant 2, mRNA PA

EST sequences (10 of 398) [Show all sequences]

AA960871.1 Clone IMAGE:1564641 mixed 3' read A
AA974768.1 brain 3' read
AI041806.1 Clone IMAGE:1665425 skin 3' read A
AI055859.1 Clone IMAGE:1750196 brain 3' read A
R20614.1 Clone IMAGE:36259 brain 5' read P
CB050434.1 Clone IMAGE:3272104 prostate 3' read A
CB050435.1 Clone IMAGE:3272104 prostate 5' read
AI150163.1 Clone IMAGE:1751900 testis 3' read A
AI160864.1 Clone IMAGE:1705010 heart 3' read A
AI160632.1 Clone IMAGE:1716339 placenta 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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