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UGID:154918     UniGene Hs.156832     Homo sapiens (human)   NPAS2
Neuronal PAS domain protein 2 (NPAS2)

Human protein-coding gene NPAS2. Represented by 203 ESTs from 106 cDNA libraries. Corresponds to reference sequence NM_002518.3. [UniGene 154918 - Hs.156832]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003309214.1 PREDICTED: neuronal PAS domain-containing protein 2 isoform 2 P. troglodytes 100.0 888
NP_002509.2 NPAS2 gene product H. sapiens 100.0 823
XP_001105763.2 PREDICTED: neuronal PAS domain-containing protein 2-like isoform 2 M. mulatta 99.7 888
XP_003909088.1 PREDICTED: neuronal PAS domain-containing protein 2 isoform 2 P. anubis 99.5 888
NP_032745.2 Npas2 gene product M. musculus 93.1 815
NP_001083854.2 clock homolog X. laevis 65.8 811
NP_840084.1 npas2 gene product D. rerio 65.1 811
NP_523964.2 clock, isoform A D. melanogaster 58.2 388
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
XP_531781.2 PREDICTED: neuronal PAS domain-containing protein 2 C. lupus familiaris 95.0 831
NP_001077232.1 NPAS2 gene product B. taurus 93.5 803

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; brain; mixed; liver; pharynx; adrenal gland; mouth; skin; intestine; kidney; prostate; testis; pancreas; embryonic tissue; muscle; placenta; eye; uterus; mammary gland; stomach; thyroid; connective tissue; ovary; bladder; trachea; vascular; ascites; bone; heart; larynx; uncharacterized tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q11.2
UniSTS entry: Chr 2 RH77872
UniSTS entry: RH79879
UniSTS entry: Chr 2 RH71260
UniSTS entry: Chr 9 RH47306 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BC051351.1 Homo sapiens neuronal PAS domain protein 2, mRNA (cDNA clone MGC:59643 IMAGE:6538324), complete cds PA
AK128586.1 Homo sapiens cDNA FLJ46745 fis, clone TRACH3021883, moderately similar to Neuronal PAS domain protein 2 P
NM_002518.3 Homo sapiens neuronal PAS domain protein 2 (NPAS2), mRNA P
BC072383.1 Homo sapiens neuronal PAS domain protein 2, mRNA (cDNA clone MGC:71151 IMAGE:6371187), complete cds PA
AK226093.1 Homo sapiens mRNA for neuronal PAS domain protein 2 variant, clone: ef04754 P
AK095806.1 Homo sapiens cDNA FLJ38487 fis, clone FEBRA2023377, highly similar to NEURONAL PAS DOMAIN PROTEIN 2 P
AK091939.1 Homo sapiens cDNA FLJ34620 fis, clone KIDNE2014789, highly similar to NEURONAL PAS DOMAIN PROTEIN 2 P
BC028107.1 Homo sapiens neuronal PAS domain protein 2, mRNA (cDNA clone IMAGE:5248433), partial cds P
U51625.1 Human MOP4 mRNA, partial cds P
AK294733.1 Homo sapiens cDNA FLJ59682 complete cds, highly similar to Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4) P
U77970.1 Human neuronal PAS2 (NPAS2) mRNA, complete cds P

EST sequences (10 of 203) [Show all sequences]

AA885624.1 Clone IMAGE:1499949 lung 3' read P
AI017409.1 Clone IMAGE:1635323 kidney 3' read P
BX103555.1 Clone IMAGp998O07672_;_IMAGE:300510 lung A
AI168775.1 Clone IMAGE:1661749 mixed 3' read A
AI242839.1 Clone IMAGE:1857813 mixed 3' read P
AI310356.1 Clone IMAGE:1913503 intestine 3' read P
AI363340.1 Clone IMAGE:2016148 brain 3' read A
AI417134.1 Clone IMAGE:2114596 mixed 3' read
AI417835.1 Clone IMAGE:2114279 mixed 3' read A
AI420598.1 Clone IMAGE:2095587 prostate 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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