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UGID:154270     UniGene Hs.153952     Homo sapiens (human)   NT5E
5'-nucleotidase, ecto (CD73) (NT5E)

Human protein-coding gene NT5E. Represented by 495 ESTs from 174 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 154270 - Hs.153952]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_518619.3 PREDICTED: 5'-nucleotidase isoform 2 P. troglodytes 100.0 573
NP_002517.1 NT5E gene product H. sapiens 100.0 573
XP_001086989.1 PREDICTED: 5'-nucleotidase isoform 3 M. mulatta 99.8 573
XP_003897912.1 PREDICTED: 5'-nucleotidase isoform 1 P. anubis 99.8 573
NP_035981.1 Nt5e gene product M. musculus 91.5 575
NP_001089463.1 5'-nucleotidase, ecto (CD73) precursor X. laevis 72.4 576
NP_957226.1 nt5e gene product D. rerio 71.5 564
NP_725682.2 CG30103 D. melanogaster 49.0 255
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
XP_001927130.1 PREDICTED: 5'-nucleotidase isoform 1 S. scrofa 94.1 573
XP_532221.2 PREDICTED: 5'-nucleotidase C. lupus familiaris 93.7 460

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; skin; lung; uterus; placenta; kidney; testis; connective tissue; vascular; uncharacterized tissue; embryonic tissue; intestine; lymph node; mammary gland; mixed; thyroid; liver; blood; esophagus; spleen; trachea; eye; ovary; mouth; prostate; ganglia; cervix; pancreas; stomach; muscle; bladder; heart; bone marrow; amniotic fluid; bone; thymus; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6q14-q21
UniSTS entry: Chr 6 RH46710
UniSTS entry: Chr 6 STS-X55740 [Map Viewer]
UniSTS entry: Chr 6 D6S1847 [Map Viewer]
UniSTS entry: Chr 6 WI-20546 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_002526.3 Homo sapiens 5'-nucleotidase, ecto (CD73) (NT5E), transcript variant 1, mRNA PA
BC065937.1 Homo sapiens 5'-nucleotidase, ecto (CD73), mRNA (cDNA clone MGC:75146 IMAGE:6163101), complete cds PA
X55740.1 Human placental cDNA coding for 5'nucleotidase (EC 3.1.3.5) P
DQ186653.1 Homo sapiens liver ecto-5'-nucleotidase (NT5E) mRNA, complete cds P
BC015940.1 Homo sapiens 5'-nucleotidase, ecto (CD73), mRNA (cDNA clone IMAGE:3920680), complete cds PA
AK314661.1 Homo sapiens cDNA, FLJ95508, highly similar to Homo sapiens 5'-nucleotidase, ecto (CD73) (NT5E), mRNA P
AK075083.1 Homo sapiens cDNA FLJ90602 fis, clone PLACE1001464, highly similar to 5'-nucleotidase precursor (EC 3.1.3.5) P
AK075008.1 Homo sapiens cDNA FLJ90527 fis, clone NT2RP4001467, highly similar to 5'-nucleotidase precursor (EC 3.1.3.5) PA
NM_001204813.1 Homo sapiens 5'-nucleotidase, ecto (CD73) (NT5E), transcript variant 2, mRNA PA

EST sequences (10 of 495) [Show all sequences]

AI073668.1 Clone IMAGE:1664361 skin 3' read
R23041.1 Clone IMAGE:130993 placenta 5' read
CB050289.1 Clone IMAGE:3271685 prostate 3' read
CB051958.1 Clone IMAGE:3290008 uncharacterized tissue 3' read A
CB051959.1 Clone IMAGE:3290008 uncharacterized tissue 5' read
BX117470.1 Clone IMAGp998F0769_;_IMAGE:21655 brain A
AI184750.1 Clone IMAGE:1723486 placenta 3' read A
AI202304.1 Clone IMAGE:1943454 prostate 3' read A
CB157450.1 Clone L17N670205n1-9-G07 liver 5' read
CB126791.1 Clone L5HLK1s1-25-H08 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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