NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:152706     UniGene Hs.147643     Homo sapiens (human)   SH2D4B
SH2 domain containing 4B (SH2D4B)

Human protein-coding gene SH2D4B. Represented by 11 ESTs from 8 cDNA libraries. EST representation biased toward spleen. Corresponds to 2 reference sequences (different isoforms). [UniGene 152706 - Hs.147643]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_997255.2 SH2D4B gene product H. sapiens 100.0 356
NP_808484.2 Sh2d4b gene product M. musculus 92.7 328
XP_689048.4 PREDICTED: SH2 domain-containing protein 4B-like D. rerio 58.0 352
Other hits (2 of 17) [Show all]SpeciesId(%)Len(aa)
XP_001153936.1 PREDICTED: SH2 domain-containing protein 4B isoform 2 P. troglodytes 98.9 356
XP_003903738.1 PREDICTED: SH2 domain-containing protein 4B isoform 1 P. anubis 96.9 356

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: spleen [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; spleen; mixed
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q23.1
UniSTS entry: Chr 10 SH2D4B__5396
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

AK123978.1 Homo sapiens cDNA FLJ41984 fis, clone SPLEN2011422, weakly similar to CALDESMON P
AK123885.1 Homo sapiens cDNA FLJ41891 fis, clone OCBBF2025028 P
NM_207372.2 Homo sapiens SH2 domain containing 4B (SH2D4B), transcript variant 1, mRNA PA
AK091518.1 Homo sapiens cDNA FLJ34199 fis, clone FCBBF3019570
NM_001145719.1 Homo sapiens SH2 domain containing 4B (SH2D4B), transcript variant 2, mRNA PA

EST sequences (11)

BX103545.1 Clone IMAGp998P144454_;_IMAGE:1752829 testis
AW511015.1 Clone IMAGE:2912176 mixed 3' read
DA180313.1 Clone BRAMY2044970 brain 5' read
DA504390.1 Clone FCBBF3019570 brain 5' read
DA787477.1 Clone OCBBF2025028 brain 5' read
DA938279.1 Clone SPLEN2011422 spleen 5' read P
DB316020.1 Clone FCBBF3019570 brain 3' read A
DB088096.1 Clone TESTI4036219 testis 5' read
DB332990.1 Clone SPLEN2011422 spleen 3' read A
DB326463.1 Clone OCBBF2025028 brain 3' read A
HY229935.1 Clone H04D153E08 testis


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help