NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy

Query Tips
Build Info
Library Browser
Download UniGene

Related Databases

NIH cDNA Projects
Finding cDNAs

UGID:152706     UniGene Hs.147643     Homo sapiens (human)   SH2D4B
SH2 domain containing 4B (SH2D4B)

Human protein-coding gene SH2D4B. Represented by 11 ESTs from 8 cDNA libraries. EST representation biased toward spleen. Corresponds to 2 reference sequences (different isoforms). [UniGene 152706 - Hs.147643]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_997255.2 SH2D4B gene product H. sapiens 100.0 356
NP_808484.2 Sh2d4b gene product M. musculus 92.7 328
XP_689048.4 PREDICTED: SH2 domain-containing protein 4B-like D. rerio 58.0 352
Other hits (2 of 17) [Show all]SpeciesId(%)Len(aa)
XP_001153936.1 PREDICTED: SH2 domain-containing protein 4B isoform 2 P. troglodytes 98.9 356
XP_003903738.1 PREDICTED: SH2 domain-containing protein 4B isoform 1 P. anubis 96.9 356

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: spleen [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; spleen; mixed
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q23.1
UniSTS entry: Chr 10 SH2D4B__5396
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

AK123978.1 Homo sapiens cDNA FLJ41984 fis, clone SPLEN2011422, weakly similar to CALDESMON P
AK123885.1 Homo sapiens cDNA FLJ41891 fis, clone OCBBF2025028 P
NM_207372.2 Homo sapiens SH2 domain containing 4B (SH2D4B), transcript variant 1, mRNA PA
AK091518.1 Homo sapiens cDNA FLJ34199 fis, clone FCBBF3019570
NM_001145719.1 Homo sapiens SH2 domain containing 4B (SH2D4B), transcript variant 2, mRNA PA

EST sequences (11)

BX103545.1 Clone IMAGp998P144454_;_IMAGE:1752829 testis
AW511015.1 Clone IMAGE:2912176 mixed 3' read
DA180313.1 Clone BRAMY2044970 brain 5' read
DA504390.1 Clone FCBBF3019570 brain 5' read
DA787477.1 Clone OCBBF2025028 brain 5' read
DA938279.1 Clone SPLEN2011422 spleen 5' read P
DB316020.1 Clone FCBBF3019570 brain 3' read A
DB088096.1 Clone TESTI4036219 testis 5' read
DB332990.1 Clone SPLEN2011422 spleen 3' read A
DB326463.1 Clone OCBBF2025028 brain 3' read A
HY229935.1 Clone H04D153E08 testis

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help