NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:130990     UniGene Hs.1376     Homo sapiens (human)   HSD11B2
Hydroxysteroid (11-beta) dehydrogenase 2 (HSD11B2)

Human protein-coding gene HSD11B2. Represented by 181 ESTs from 82 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_000196.3. [UniGene 130990 - Hs.1376]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000187.3 HSD11B2 gene product H. sapiens 100.0 404
XP_523393.2 PREDICTED: corticosteroid 11-beta-dehydrogenase isozyme 2 isoform 2 P. troglodytes 99.8 404
NP_032315.2 Hsd11b2 gene product M. musculus 90.2 385
NP_001086062.1 hydroxysteroid (11-beta) dehydrogenase 2 X. laevis 54.7 373
NP_997885.2 corticosteroid 11-beta-dehydrogenase isozyme 2 D. rerio 53.7 380
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_001088119.2 PREDICTED: corticosteroid 11-beta-dehydrogenase isozyme 2 M. mulatta 99.2 401
XP_003917091.1 PREDICTED: corticosteroid 11-beta-dehydrogenase isozyme 2 P. anubis 99.0 404

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; intestine; testis; eye; ascites; mixed; mammary gland; kidney; thyroid; trachea; bladder; brain; uncharacterized tissue; lung; stomach; prostate; liver; uterus; heart; spleen; connective tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16q22
UniSTS entry: Chr 16 RH70275 [Map Viewer]
UniSTS entry: Chr 16 RH64980
UniSTS entry: Chr 16 WI-9392 [Map Viewer]
UniSTS entry: Chr 16 SHGC-33002 [Map Viewer]
UniSTS entry: Chr 1 MARC_5745-5746:996690776:3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

NM_000196.3 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 2 (HSD11B2), mRNA PA
BC064536.1 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 2, mRNA (cDNA clone MGC:70817 IMAGE:5722669), complete cds PA
U14631.1 Human 11 beta-hydroxysteroid dehydrogenase type II mRNA, complete cds P
U26726.1 Human 11-beta-hydroxysteroid dehydrogenase type 2 mRNA, complete cds P
BC036780.1 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 2, mRNA (cDNA clone MGC:46217 IMAGE:5725938), complete cds PA

EST sequences (10 of 181) [Show all sequences]

AI050781.1 Clone IMAGE:1637072 kidney 3' read A
R21520.1 Clone IMAGE:130180 placenta 3' read
R21622.1 Clone IMAGE:130180 placenta 5' read P
AI127112.1 Clone IMAGE:1708120 heart 3' read A
R23749.1 Clone IMAGE:131645 placenta 3' read A
R23802.1 Clone IMAGE:131645 placenta 5' read
AI149588.1 Clone IMAGE:1713991 placenta 3' read A
AI151214.1 Clone IMAGE:1715297 placenta 3' read A
BX091870.1 Clone IMAGp998P05202_;_IMAGE:139252 placenta A
AI189990.1 Clone IMAGE:1724730 placenta 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help