NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy

Query Tips
Build Info
Library Browser
Download UniGene

Related Databases

NIH cDNA Projects
Finding cDNAs

UGID:130990     UniGene Hs.1376     Homo sapiens (human)   HSD11B2
Hydroxysteroid (11-beta) dehydrogenase 2 (HSD11B2)

Human protein-coding gene HSD11B2. Represented by 181 ESTs from 82 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_000196.3. [UniGene 130990 - Hs.1376]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000187.3 HSD11B2 gene product H. sapiens 100.0 404
XP_523393.2 PREDICTED: corticosteroid 11-beta-dehydrogenase isozyme 2 isoform 2 P. troglodytes 99.8 404
NP_032315.2 Hsd11b2 gene product M. musculus 90.2 385
NP_001086062.1 hydroxysteroid (11-beta) dehydrogenase 2 X. laevis 54.7 373
NP_997885.2 corticosteroid 11-beta-dehydrogenase isozyme 2 D. rerio 53.7 380
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_001088119.2 PREDICTED: corticosteroid 11-beta-dehydrogenase isozyme 2 M. mulatta 99.2 401
XP_003917091.1 PREDICTED: corticosteroid 11-beta-dehydrogenase isozyme 2 P. anubis 99.0 404

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; intestine; testis; eye; ascites; mixed; mammary gland; kidney; thyroid; trachea; bladder; brain; uncharacterized tissue; lung; stomach; prostate; liver; uterus; heart; spleen; connective tissue
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16q22
UniSTS entry: Chr 16 RH70275 [Map Viewer]
UniSTS entry: Chr 16 RH64980
UniSTS entry: Chr 16 WI-9392 [Map Viewer]
UniSTS entry: Chr 16 SHGC-33002 [Map Viewer]
UniSTS entry: Chr 1 MARC_5745-5746:996690776:3
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

NM_000196.3 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 2 (HSD11B2), mRNA PA
BC064536.1 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 2, mRNA (cDNA clone MGC:70817 IMAGE:5722669), complete cds PA
U14631.1 Human 11 beta-hydroxysteroid dehydrogenase type II mRNA, complete cds P
U26726.1 Human 11-beta-hydroxysteroid dehydrogenase type 2 mRNA, complete cds P
BC036780.1 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 2, mRNA (cDNA clone MGC:46217 IMAGE:5725938), complete cds PA

EST sequences (10 of 181) [Show all sequences]

AI050781.1 Clone IMAGE:1637072 kidney 3' read A
R21520.1 Clone IMAGE:130180 placenta 3' read
R21622.1 Clone IMAGE:130180 placenta 5' read P
AI127112.1 Clone IMAGE:1708120 heart 3' read A
R23749.1 Clone IMAGE:131645 placenta 3' read A
R23802.1 Clone IMAGE:131645 placenta 5' read
AI149588.1 Clone IMAGE:1713991 placenta 3' read A
AI151214.1 Clone IMAGE:1715297 placenta 3' read A
BX091870.1 Clone IMAGp998P05202_;_IMAGE:139252 placenta A
AI189990.1 Clone IMAGE:1724730 placenta 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help