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UGID:150518     UniGene Hs.136295     Homo sapiens (human)   GNAL
Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (GNAL)

Human protein-coding gene GNAL. Represented by 186 ESTs from 94 cDNA libraries. EST representation biased toward fetus. Corresponds to 4 reference sequences (different isoforms). [UniGene 150518 - Hs.136295]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_892023.1 GNAL gene product H. sapiens 100.0 457
XP_001172063.1 PREDICTED: guanine nucleotide-binding protein G(olf) subunit alpha isoform 3 P. troglodytes 100.0 380
XP_849960.1 PREDICTED: guanine nucleotide-binding protein G(olf) subunit alpha isoform 2 C. lupus familiaris 100.0 379
XP_004020693.1 PREDICTED: guanine nucleotide-binding protein G(olf) subunit alpha, partial O. aries 100.0 342
XP_003365611.1 PREDICTED: guanine nucleotide-binding protein G(olf) subunit alpha-like E. caballus 100.0 319
NP_001096024.1 GNAL gene product B. taurus 99.7 379
NP_796111.2 Gnal gene product M. musculus 98.4 447
NP_001079318.1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type X. laevis 91.3 378
NP_001007340.1 gnal gene product D. rerio 88.7 378
NP_477506.1 G protein salpha 60A, isoform A D. melanogaster 75.4 381
NP_490817.3 Protein GSA-1 C. elegans 68.5 374
XP_962205.1 guanine nucleotide-binding protein alpha-3 subunit N. crassa 48.6 140
Other hits (2 of 40) [Show all]SpeciesId(%)Len(aa)
XP_003914191.1 PREDICTED: guanine nucleotide-binding protein G(olf) subunit alpha P. anubis 99.1 449
XP_002713606.1 PREDICTED: guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type isoform 1 O. cuniculus 98.7 451

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: fetus [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; testis; lung; uncharacterized tissue; embryonic tissue; placenta; heart; mouth; connective tissue; prostate; thymus; skin; trachea; ear; pancreas; uterus; liver; eye; pituitary gland; intestine; bladder; vascular
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18p11.22-p11.21
UniSTS entry: Chr 18 WI-15313 [Map Viewer]
UniSTS entry: Chr 18 WI-20459 [Map Viewer]
UniSTS entry: Chr 18 D18S1193
UniSTS entry: Chr 18 STS-N37055 [Map Viewer]
UniSTS entry: Chr 18 SGC30688 [Map Viewer]
UniSTS entry: Chr 18 D18S1241 [Map Viewer]
UniSTS entry: Chr 18 WI-12711 [Map Viewer]
UniSTS entry: Chr 18 GNAL__7520
UniSTS entry: D18S1241
UniSTS entry: Chr 18 RH68711 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BC050021.1 Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type, mRNA (cDNA clone MGC:51307 IMAGE:5297878), complete cds PA
NM_182978.3 Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (GNAL), transcript variant 1, mRNA PA
L10665.1 Human GTP-binding protein superfamily, G protein alpha-olf subunit (olfactory) mRNA, complete cds P
AK290054.1 Homo sapiens cDNA FLJ78702 complete cds, highly similar to Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (GNAL), transcript variant 2, mRNA P
AK313902.1 Homo sapiens cDNA, FLJ94539, Homo sapiens guanine nucleotide binding protein (G protein), alphaactivating activity polypeptide, olfactory type (GNAL), transcriptvariant 2, mRNA P
AK307260.1 Homo sapiens cDNA, FLJ97208 P
AF493893.1 Homo sapiens guanine nucleotide binding protein alpha olf (GNAL) mRNA, complete cds P
AK090868.1 Homo sapiens cDNA FLJ33549 fis, clone BRAMY2009013, highly similar to GUANINE NUCLEOTIDE-BINDING PROTEIN G P
AK295088.1 Homo sapiens cDNA FLJ55310 complete cds, highly similar to Guanine nucleotide-binding protein G(olf) subunit alpha P
NM_001142339.2 Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (GNAL), transcript variant 3, mRNA PA
AK316141.1 Homo sapiens cDNA, FLJ79040 complete cds, highly similar to Guanine nucleotide-binding protein G(olf) subunit alpha P
NM_001261443.1 Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (GNAL), transcript variant 4, mRNA PA
NM_001261444.1 Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (GNAL), transcript variant 5, mRNA PA

EST sequences (10 of 186) [Show all sequences]

AA973921.1 Clone IMAGE:1569470 lung 3' read
AI024119.1 Clone IMAGE:1643585 testis 3' read
R20102.1 Clone IMAGE:35031 brain 5' read
AI078763.1 Clone IMAGE:1677210 mixed 3' read
AI082827.1 Clone IMAGE:1662425 mixed 3' read
BX097239.1 Clone IMAGp998O031852_;_IMAGE:753626 mixed
BX103980.1 Clone IMAGp998J131814_;_IMAGE:738924 mixed
BX107392.1 Clone IMAGp998N084538_;_IMAGE:1854535 mixed P
AI217380.1 Clone IMAGE:1844941 mixed 3' read P
CB118067.1 Clone B1T694954-9-G09 brain 5' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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