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UGID:148295     UniGene Hs.128959     Homo sapiens (human)   PCF11
PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae) (PCF11)

Human protein-coding gene PCF11. Represented by 312 ESTs from 179 cDNA libraries. Corresponds to reference sequence NM_015885.3. [UniGene 148295 - Hs.128959]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_056969.2 PCF11 gene product H. sapiens 100.0 1554
XP_003910536.1 PREDICTED: pre-mRNA cleavage complex 2 protein Pcf11 P. anubis 99.6 1554
NP_083354.3 pre-mRNA cleavage complex II protein Pcf11 M. musculus 96.3 1552
NP_001007308.1 pcf11 gene product D. rerio 67.2 1437
NP_001188931.1 inverse regulator a, isoform E D. melanogaster 49.7 155
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
XP_508673.4 PREDICTED: pre-mRNA cleavage complex 2 protein Pcf11 P. troglodytes 99.4 1592
XP_002808130.1 PREDICTED: LOW QUALITY PROTEIN: pre-mRNA cleavage complex 2 protein Pcf11-like M. mulatta 98.8 1630

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; intestine; pancreas; mixed; prostate; placenta; muscle; adipose tissue; uterus; mammary gland; lung; embryonic tissue; liver; eye; mouth; blood; nerve; ovary; heart; cervix; pituitary gland; trachea; bladder; connective tissue; larynx; skin; lymph node; thymus; thyroid; kidney; stomach; esophagus; pharynx; ascites; bone marrow; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q13
UniSTS entry: Chr 11 WI-11852 [Map Viewer]
UniSTS entry: Chr 11 RH78058
UniSTS entry: Chr 11 A007H35
UniSTS entry: Chr 11 MARC_14809-14810:1027964802:1
UniSTS entry: Chr 11 RH11546
UniSTS entry: Chr 11 RH46125
UniSTS entry: Chr 11 ksks262
UniSTS entry: Chr 11 RH46173
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AB020631.1 Homo sapiens mRNA for KIAA0824 protein, partial cds P
BC065384.1 Homo sapiens PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae), mRNA (cDNA clone MGC:65021 IMAGE:6043635), complete cds PA
NM_015885.3 Homo sapiens PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae) (PCF11), mRNA PA
AK025103.1 Homo sapiens cDNA: FLJ21450 fis, clone COL04486 PA
BC110432.1 Homo sapiens PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:5529131), partial cds PA
BC146778.1 Homo sapiens PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae), mRNA (cDNA clone MGC:166858 IMAGE:9007228), complete cds PA
AK302606.1 Homo sapiens cDNA FLJ61740 partial cds, highly similar to Pre-mRNA cleavage complex 2 protein Pcf11 PA
AF046935.1 Homo sapiens PCF11p homolog mRNA, complete cds PA

EST sequences (10 of 312) [Show all sequences]

AA971679.1 Clone IMAGE:1583646 mixed 3' read P
AA973337.1 Clone IMAGE:1584243 mixed 3' read PA
AA902424.1 Clone IMAGE:1521264 lung 3' read
AI039108.1 Clone IMAGE:1657605 embryonic tissue 3' read A
T06184.1 Clone HFBDP94 brain P
AI093853.1 Clone IMAGE:1688276 mixed 3' read
CB045205.1 Clone IMAGE:3218196 intestine 5' read P
CB045204.1 Clone IMAGE:3218196 intestine 3' read A
CB066762.1 Clone IMAGE: pancreas 3' read PA
CB067026.1 Clone IMAGE: pancreas 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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