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UGID:148151     UniGene Hs.128548     Homo sapiens (human)   WDR1
WD repeat domain 1 (WDR1)

Human protein-coding gene WDR1. Represented by 1882 ESTs from 479 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 148151 - Hs.128548]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001158453.1 PREDICTED: WD repeat-containing protein 1 isoform 7 P. troglodytes 100.0 609
NP_059830.1 WDR1 gene product H. sapiens 100.0 605
XP_003898532.1 PREDICTED: WD repeat-containing protein 1 isoform 1 P. anubis 99.7 605
NP_035845.1 Wdr1 gene product M. musculus 97.4 605
NP_001083198.1 WD repeat-containing protein 1-B X. laevis 87.0 606
NP_957333.1 wdr1 gene product D. rerio 81.3 605
NP_648642.1 flare, isoform A D. melanogaster 59.8 605
NP_001024357.1 Protein UNC-78, isoform b C. elegans 57.8 332
XP_957583.1 hypothetical protein NCU03944 N. crassa 52.4 328
NP_188434.2 transducin/WD40 domain-containing protein A. thaliana 49.6 351
Other hits (2 of 51) [Show all]SpeciesId(%)Len(aa)
XP_001097741.1 PREDICTED: WD repeat-containing protein 1 isoform 4 M. mulatta 99.4 332
NP_001124309.1 WDR1 gene product C. lupus familiaris 98.7 605

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; kidney; skin; testis; uncharacterized tissue; intestine; lung; uterus; embryonic tissue; thymus; connective tissue; placenta; vascular; blood; eye; pancreas; stomach; mixed; mammary gland; liver; thyroid; spleen; ovary; prostate; lymph node; mouth; tonsil; umbilical cord; trachea; bone; heart; cervix; amniotic fluid; adipose tissue; ganglia; esophagus; salivary gland; parathyroid; ear; ascites; lymph; bone marrow; bladder; muscle; larynx; nerve; pharynx; pituitary gland; spinal cord; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4p16.1
UniSTS entry: Chr 4 SHGC-67857
UniSTS entry: Chr 4 SHGC-67675 [Map Viewer]
UniSTS entry: Chr 4 SHGC-33408 [Map Viewer]
UniSTS entry: Chr 4 D1S3699
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

AB010427.2 Homo sapiens mRNA for NORI-1, complete cds PA
AF020056.1 Homo sapiens WDR1 protein mRNA, complete cds PA
AF020260.1 Homo sapiens WDR1 protein mRNA, complete cds PA
AL050108.1 Homo sapiens mRNA; cDNA DKFZp586I2219 (from clone DKFZp586I2219) PA
AL110208.1 Homo sapiens mRNA; cDNA DKFZp586P1922 (from clone DKFZp586P1922) PA
BX648190.1 Homo sapiens mRNA; cDNA DKFZp686J1427 (from clone DKFZp686J1427) PA
AK127665.1 Homo sapiens cDNA FLJ45763 fis, clone N1ESE2000698, highly similar to WD repeat protein 1 P
NM_005112.4 Homo sapiens WD repeat domain 1 (WDR1), transcript variant 2, mRNA PA
NM_017491.3 Homo sapiens WD repeat domain 1 (WDR1), transcript variant 1, mRNA PA
AB209746.1 Homo sapiens mRNA for WD repeat-containing protein 1 isoform 1 variant protein P
AK222897.1 Homo sapiens mRNA for WD repeat-containing protein 1 isoform 1 variant, clone: HRC01041 P
AK222764.1 Homo sapiens mRNA for WD repeat-containing protein 1 isoform 1 variant, clone: HEP00464 P
BC002489.2 Homo sapiens WD repeat domain 1, mRNA (cDNA clone MGC:1382 IMAGE:3051319), complete cds PA
BC000201.1 Homo sapiens WD repeat domain 1, mRNA (cDNA clone MGC:3118 IMAGE:3351638), complete cds PA
AK225276.1 Homo sapiens mRNA for WD repeat-containing protein 1 isoform 1 variant, clone: HEP00464 P
AF274954.1 Homo sapiens PNAS-29 mRNA, complete cds PA
AK291614.1 Homo sapiens cDNA FLJ76314 complete cds, highly similar to Homo sapiens WD repeat domain 1 (WDR1), transcript variant 1, mRNA P
BC030541.2 Homo sapiens WD repeat domain 1, mRNA (cDNA clone MGC:40281 IMAGE:4403484), complete cds PA
AL832280.1 Homo sapiens mRNA; cDNA DKFZp667F2018 (from clone DKFZp667F2018) A
AK299602.1 Homo sapiens cDNA FLJ57081 complete cds, moderately similar to WD repeat protein 1 P
AK303132.1 Homo sapiens cDNA FLJ59130 complete cds, moderately similar to Homo sapiens WD repeat domain 1 (WDR1), transcript variant 2, mRNA P
AK302209.1 Homo sapiens cDNA FLJ58303 complete cds, highly similar to WD repeat protein 1 P
HQ013239.1 Homo sapiens clone pSWC4-5 minisatellite-associated sequence

EST sequences (10 of 1882) [Show all sequences]

AA864346.1 Clone IMAGE:1470464 uncharacterized tissue 3' read P
AA962535.1 Clone IMAGE:1602195 lung 3' read A
R17965.1 Clone IMAGE:32482 brain 5' read
AI016501.1 Clone IMAGE:1618330 testis 3' read A
AA922685.1 Clone IMAGE:1551753 uncharacterized tissue 3' read A
AI026935.1 Clone IMAGE:1643837 testis 3' read A
AI033221.1 Clone IMAGE:1654843 mixed 3' read
AI066410.1 Clone IMAGE:1682072 skin 3' read A
AI074419.1 Clone IMAGE:1679223 skin 3' read A
AI074421.1 Clone IMAGE:1679227 skin 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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