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UGID:146623     UniGene Hs.123659     Homo sapiens (human)   SMPDL3B
Sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B)

Human protein-coding gene SMPDL3B. Represented by 125 ESTs from 72 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 146623 - Hs.123659]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055289.2 SMPDL3B gene product H. sapiens 100.0 454
XP_001151336.1 PREDICTED: sphingomyelin phosphodiesterase, acid-like 3B isoform 2 P. troglodytes 99.8 454
NP_598649.1 Smpdl3b gene product M. musculus 83.2 453
XP_692822.2 PREDICTED: acid sphingomyelinase-like phosphodiesterase 3b-like D. rerio 59.6 441
Other hits (2 of 23) [Show all]SpeciesId(%)Len(aa)
XP_003891488.1 PREDICTED: LOW QUALITY PROTEIN: acid sphingomyelinase-like phosphodiesterase 3b P. anubis 90.0 460
XP_003638967.1 PREDICTED: acid sphingomyelinase-like phosphodiesterase 3b-like C. lupus familiaris 87.3 434

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; brain; esophagus; connective tissue; bone marrow; ovary; embryonic tissue; prostate; lung; kidney; placenta; liver; uncharacterized tissue; bladder; testis; mixed; cervix; trachea; pancreas; mammary gland; uterus; parathyroid; ascites; stomach; spleen; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p35.3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_014474.2 Homo sapiens sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B), transcript variant 1, mRNA PA
NM_001009568.1 Homo sapiens sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B), transcript variant 2, mRNA PA
BC014444.1 Homo sapiens sphingomyelin phosphodiesterase, acid-like 3B, mRNA (cDNA clone MGC:22988 IMAGE:4865268), complete cds PA
AK301349.1 Homo sapiens cDNA FLJ56798 complete cds, highly similar to Acid sphingomyelinase-like phosphodiesterase 3b precursor (EC 3.1.4.-) P
AK293566.1 Homo sapiens cDNA FLJ61214 complete cds, highly similar to Acid sphingomyelinase-like phosphodiesterase 3b precursor (EC 3.1.4.-) P
AK293489.1 Homo sapiens cDNA FLJ57705 complete cds, highly similar to Acid sphingomyelinase-like phosphodiesterase 3b precursor (EC 3.1.4.-) P
Y08134.1 H.sapiens mRNA for ASM-like phosphodiesterase 3b P
AK316500.1 Homo sapiens cDNA, FLJ79399 complete cds, highly similar to Acid sphingomyelinase-like phosphodiesterase 3b precursor (EC 3.1.4.-) PA

EST sequences (10 of 125) [Show all sequences]

AI027472.1 Clone IMAGE:1646027 parathyroid 3' read
CB069381.1 Clone IMAGE:6364878 pancreas 5' read P
BX091309.1 Clone IMAGp998L14728_;_IMAGE:321949 parathyroid P
CB160850.1 Clone L18POOL1n1-33-F05 liver 5' read P
CB142616.1 Clone L11SNU354s1-12-A02 liver 5' read P
CB144866.1 Clone L11SNU354s1-27-D10 liver 5' read P
AI273418.1 Clone IMAGE:1872705 intestine 3' read
AI335007.1 Clone IMAGE:2055001 kidney 3' read
AI492184.1 Clone IMAGE:2108104 uncharacterized tissue 3' read P
AI859716.1 Clone IMAGE:2436428 uterus 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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