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UGID:146366     UniGene Hs.122926     Homo sapiens (human)   NR3C1
Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1)

Human protein-coding gene NR3C1. Represented by 474 ESTs from 217 cDNA libraries. Corresponds to 15 reference sequences (different isoforms). [UniGene 146366 - Hs.122926]

SELECTED PROTEIN SIMILARITIES
GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; placenta; mixed; lung; testis; pancreas; kidney; pituitary gland; mouth; liver; prostate; muscle; heart; skin; uterus; thymus; connective tissue; bone; lymph node; salivary gland; vascular; blood; cervix; pharynx; intestine; thyroid; bone marrow; trachea; ear; eye; embryonic tissue; mammary gland; ovary; stomach; lymph; esophagus; adipose tissue; nerve; parathyroid; spleen
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q31.3
UniSTS entry: Chr 5 PMC64995P2
UniSTS entry: Chr 5 NR3C1
UniSTS entry: Chr 5 D5S2472 [Map Viewer]
UniSTS entry: Chr 5 NR3C1_1004
UniSTS entry: Chr 5 WI-20193 [Map Viewer]
UniSTS entry: Chr 5 Nr3c1
UniSTS entry: Chr 5 STS-U25029 [Map Viewer]
UniSTS entry: Nr3c1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (38)

BX648553.1 Homo sapiens mRNA; cDNA DKFZp779N1540 (from clone DKFZp779N1540) PA
BX640610.1 Homo sapiens mRNA; cDNA DKFZp686J22179 (from clone DKFZp686J22179) PA
NM_000176.2 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 1, mRNA P
AK223594.1 Homo sapiens mRNA for nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) variant, clone: FCC131A06 P
NM_001024094.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 7, mRNA P
NM_001020825.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 6, mRNA P
NM_001018077.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 5, mRNA P
NM_001018076.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 4, mRNA P
NM_001018075.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 3, mRNA P
NM_001018074.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 2, mRNA P
AJ888004.1 Homo sapiens partial mRNA for nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1 gene) splice variant 1G P
AJ877172.1 Homo sapiens partial mRNA for nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1 gene), splice variant 1C3 P
AJ877171.1 Homo sapiens partial mRNA for nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1 gene), splice variant 1C2 P
AJ877170.1 Homo sapiens partial mRNA for nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1 gene), splice variant 1C1 P
AJ877169.1 Homo sapiens partial mRNA for nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1 gene), splice variant 1H P
AJ877168.1 Homo sapiens partial mRNA for nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1 gene), splice variant 1F P
AJ877167.1 Homo sapiens partial mRNA for nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1 gene), splice variant 1E P
AJ877166.1 Homo sapiens partial mRNA for nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1 gene), splice variant 1D P
AM183262.1 Homo sapiens mRNA for glucocorticoid receptor (NR3C1 gene), [delta]313-338 isoform P
BC015610.2 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), mRNA (cDNA clone MGC:23072 IMAGE:4810424), complete cds PA
AK314789.1 Homo sapiens cDNA, FLJ95659 P
X03225.1 Human mRNA for alpha-glucocorticoid receptor (clone OB7) P
X03348.1 Human mRNA for beta-glucocorticoid receptor (clone OB10) P
U01351.1 Human glucocorticoid receptor alpha-2 mRNA, complete cds P
AB307716.1 Homo sapiens NR3C1 mRNA for glucocorticoid receptor, complete cds P
AK302050.1 Homo sapiens cDNA FLJ50281 complete cds, highly similar to Glucocorticoid receptor P
U25029.1 Human glucocorticoid receptor alpha mRNA, variant 3' UTR
NM_001204265.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 8, mRNA P
NM_001204264.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 1, mRNA PA
NM_001204263.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 1, mRNA PA
NM_001204262.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 1, mRNA PA
NM_001204261.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 1, mRNA PA
NM_001204260.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 1, mRNA PA
NM_001204259.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 1, mRNA PA
NM_001204258.1 Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 1, mRNA PA
HQ692822.1 Homo sapiens glucocorticoid nuclear receptor variant 1 (NR3C1) mRNA, complete cds P
JN797823.1 Homo sapiens isolate hGR AS-1 glucocorticoid receptor (NR3C1) mRNA, complete cds, alternatively spliced P
JN797824.1 Homo sapiens isolate hGR AS-2 glucocorticoid receptor (NR3C1) mRNA, complete cds, alternatively spliced P

EST sequences (10 of 474) [Show all sequences]

AA962235.1 Clone IMAGE:1553543 kidney 3' read A
AA971257.1 Clone IMAGE:1582484 mixed 3' read A
AA904596.1 Clone IMAGE:1503818 mixed 3' read A
AI003813.1 Clone IMAGE:1619530 testis 3' read
AA922562.1 Clone IMAGE:1551638 uncharacterized tissue 3' read A
AA927050.1 Clone IMAGE:1542190 mixed 3' read A
R19460.1 Clone IMAGE:33695 brain 5' read
AI056369.1 Clone IMAGE:1669070 brain 3' read A
AI073882.1 Clone IMAGE:1565956 mixed 3' read A
R21472.1 Clone IMAGE:31463 brain 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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