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UGID:145727     UniGene Hs.120633     Homo sapiens (human)   SESN3
Sestrin 3 (SESN3)

Human protein-coding gene SESN3. Represented by 533 ESTs from 189 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 145727 - Hs.120633]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_653266.2 SESN3 gene product H. sapiens 100.0 491
XP_001091126.1 PREDICTED: sestrin-3 isoform 5 M. mulatta 99.6 491
XP_003910622.1 PREDICTED: sestrin-3 P. anubis 99.6 491
NP_084537.2 Sesn3 gene product M. musculus 96.3 491
NP_001085478.1 sestrin-3 X. laevis 85.7 474
NP_998684.1 sesn3 gene product D. rerio 72.6 463
NP_001097437.1 sestrin, isoform B D. melanogaster 54.5 145
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
XP_594021.5 PREDICTED: sestrin-3 B. taurus 99.4 466
XP_003313313.1 PREDICTED: sestrin-3 isoform 2 P. troglodytes 99.3 456

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; mouth; embryonic tissue; intestine; pancreas; mixed; blood; lung; uterus; thymus; uncharacterized tissue; pharynx; adipose tissue; placenta; skin; kidney; ear; heart; lymph node; connective tissue; muscle; bladder; adrenal gland; mammary gland; spleen; vascular; esophagus; trachea; bone; larynx; parathyroid; salivary gland; eye; liver; prostate; stomach; nerve; thyroid; ovary; umbilical cord; lymph; pineal gland
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q21
UniSTS entry: Chr 11 RH11849 [Map Viewer]
UniSTS entry: Chr 11 RH18334 [Map Viewer]
UniSTS entry: Chr 11 SGC34501 [Map Viewer]
UniSTS entry: Chr 11 RH47318 [Map Viewer]
UniSTS entry: Chr 11 RH48984 [Map Viewer]
UniSTS entry: SHGC-57786
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BC045700.1 Homo sapiens cDNA clone IMAGE:5304069 A
BX649128.1 Homo sapiens mRNA; cDNA DKFZp686K0548 (from clone DKFZp686K0548) A
AB072894.1 Homo sapiens primary neuroblastoma cDNA, clone:Nbla10635
BC017296.2 Homo sapiens sestrin 3, mRNA (cDNA clone MGC:29667 IMAGE:5016567), complete cds PA
BC013939.1 Homo sapiens, Similar to cDNA sequence BC003348, clone IMAGE:3997920, mRNA A
NM_144665.3 Homo sapiens sestrin 3 (SESN3), transcript variant 1, mRNA P
AK096300.1 Homo sapiens cDNA FLJ38981 fis, clone NT2RI2005096, moderately similar to Homo sapiens p53 regulated PA26-T2 nuclear protein (PA26) mRNA P
AK091132.1 Homo sapiens cDNA FLJ33813 fis, clone CTONG2002744
AL832673.1 Homo sapiens mRNA; cDNA DKFZp313B1017 (from clone DKFZp313B1017) A
AF086504.1 Homo sapiens full length insert cDNA clone ZE02A06 A
AF086251.1 Homo sapiens full length insert cDNA clone ZD40A05 PA
AK302366.1 Homo sapiens cDNA FLJ58707 complete cds, highly similar to Sestrin-3 P
NM_001271594.1 Homo sapiens sestrin 3 (SESN3), transcript variant 2, mRNA P

EST sequences (10 of 533) [Show all sequences]

AA992453.1 Clone IMAGE:1602782 lung 3' read A
AI016166.1 Clone IMAGE:1622437 embryonic tissue 3' read
AA926941.1 Clone IMAGE:1552357 uncharacterized tissue 3' read A
AI023271.1 Clone IMAGE:1642236 testis 3' read A
AA928759.1 Clone IMAGE:1564706 mixed 3' read A
AI051008.1 Clone IMAGE:1648991 parathyroid 3' read A
AI150479.1 Clone IMAGE:1752074 testis 3' read A
AI190194.1 Clone IMAGE:1731660 heart 3' read
CB154139.1 Clone L17N670205-3-H12 liver 5' read
CB147680.1 Clone L14ChoiCK0-17-H02 liver 5' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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