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UGID:144497     UniGene Hs.114033     Homo sapiens (human)   SSR1
Signal sequence receptor, alpha (SSR1)

Human protein-coding gene SSR1. Represented by 1092 ESTs from 394 cDNA libraries. Corresponds to reference sequence NM_003144.3. [UniGene 144497 - Hs.114033]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001245081.1 translocon-associated protein subunit alpha precursor M. mulatta 100.0 285
XP_003897066.1 PREDICTED: translocon-associated protein subunit alpha isoform 1 P. anubis 100.0 285
XP_003311142.1 PREDICTED: translocon-associated protein subunit alpha-like P. troglodytes 100.0 285
NP_003135.2 SSR1 gene product H. sapiens 100.0 285
NP_080241.3 Ssr1 gene product M. musculus 99.0 285
NP_001079921.1 signal sequence receptor, alpha (translocon-associated protein alpha) precursor X. laevis 92.0 285
NP_958484.1 ssr1 gene product D. rerio 85.9 289
NP_572567.1 lethal (1) G0320 D. melanogaster 47.5 242
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
NP_001003270.1 SSR1 gene product C. lupus familiaris 99.3 285
NP_001172096.1 signal sequence receptor, alpha S. scrofa 99.0 285

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; liver; uncharacterized tissue; placenta; skin; connective tissue; mixed; lung; intestine; adipose tissue; muscle; mouth; mammary gland; prostate; embryonic tissue; uterus; eye; kidney; trachea; spinal cord; blood; pancreas; thymus; amniotic fluid; pharynx; vascular; lymph node; esophagus; ovary; heart; spleen; bone marrow; stomach; thyroid; ear; ascites; bone; salivary gland; bladder; cervix; nerve; umbilical cord; adrenal gland; tonsil
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p24.3
UniSTS entry: Chr 6 SGC35789 [Map Viewer]
UniSTS entry: Chr 6 A006P22
UniSTS entry: Chr 6 SHGC-32039 [Map Viewer]
UniSTS entry: Chr 6 RH17553
UniSTS entry: Chr 6 D6S321E [Map Viewer]
UniSTS entry: Chr 6 RH103606
UniSTS entry: Chr 6 WI-18513 [Map Viewer]
UniSTS entry: Chr 6 SHGC-84014
UniSTS entry: Chr 1 D8S2279
UniSTS entry: Chr 6 STS-N36801 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

BT007387.1 Homo sapiens signal sequence receptor, alpha (translocon-associated protein alpha) mRNA, complete cds P
NM_003144.3 Homo sapiens signal sequence receptor, alpha (SSR1), mRNA PA
CR456961.1 Homo sapiens full open reading frame cDNA clone RZPDo834B0119D for gene SSR1, signal sequence receptor, alpha (translocon-associated protein alpha); complete cds, incl. stopcodon P
AF156965.1 Homo sapiens translocon-associated protein alpha subunit mRNA, complete cds PA
CR936719.1 Homo sapiens mRNA; cDNA DKFZp781N23103 (from clone DKFZp781N23103) PA
AK222809.1 Homo sapiens mRNA for signal sequence receptor, alpha variant, clone: HEP04334 P
AK222762.1 Homo sapiens mRNA for signal sequence receptor, alpha variant, clone: HEP00909 P
AK024294.1 Homo sapiens cDNA FLJ14232 fis, clone NT2RP4000035
AK025753.1 Homo sapiens cDNA: FLJ22100 fis, clone HEP17127 A
AK026687.1 Homo sapiens cDNA: FLJ23034 fis, clone LNG02018 A
BC007710.2 Homo sapiens signal sequence receptor, alpha, mRNA (cDNA clone MGC:10331 IMAGE:4054116), complete cds PA
AK291550.1 Homo sapiens cDNA FLJ78242 complete cds, highly similar to Homo sapiens signal sequence receptor, alpha (translocon-associated protein alpha), mRNA P
AK312653.1 Homo sapiens cDNA, FLJ93042, highly similar to Homo sapiens signal sequence receptor, alpha (translocon-associated protein alpha) (SSR1), mRNA P
AK075562.1 Homo sapiens cDNA PSEC0262 fis, clone NT2RP3004505, highly similar to TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT PRECURSOR P
AJ420492.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 1601244 A
Z12830.1 H.sapiens mRNA for SSR alpha subunit P

EST sequences (10 of 1092) [Show all sequences]

AA989029.1 Clone IMAGE:1602370 lung 3' read P
AA993117.1 Clone IMAGE:1620135 testis 3' read
AA923534.1 Clone IMAGE:1536191 kidney 3' read A
AA927866.1 Clone IMAGE:1541372 mixed 3' read
AI016620.1 Clone IMAGE:1638858 testis 3' read P
AA922038.1 Clone IMAGE:1543947 mixed 3' read
AI034355.1 Clone IMAGE:1656904 mixed 3' read
AI041588.1 Clone IMAGE:1660378 mixed 3' read A
AI052274.1 Clone IMAGE:1670045 brain 3' read
AI075645.1 Clone IMAGE:1664412 skin 3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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