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UGID:143637     UniGene Hs.106124     Homo sapiens (human)   EPB49
Erythrocyte membrane protein band 4.9 (dematin) (EPB49)

Human protein-coding gene EPB49. Represented by 405 ESTs from 125 cDNA libraries. Corresponds to 6 reference sequences (different isoforms). [UniGene 143637 - Hs.106124]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003902547.1 PREDICTED: dematin isoform 1 P. anubis 100.0 404
XP_001152642.1 PREDICTED: dematin isoform 12 P. troglodytes 100.0 404
NP_001969.2 EPB49 gene product H. sapiens 100.0 404
NP_001239591.1 Epb4.9 gene product M. musculus 97.8 404
NP_001087804.1 MGC86227 protein X. laevis 65.3 385
NP_001188338.1 dematin D. rerio 60.8 392
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_001101612.2 PREDICTED: dematin M. mulatta 98.7 371
NP_001029603.1 EPB49 gene product B. taurus 98.0 357

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; liver; eye; mixed; bone marrow; lymph node; uncharacterized tissue; kidney; testis; ovary; pancreas; mammary gland; blood; cervix; pituitary gland; muscle; intestine; nerve; uterus; parathyroid; adrenal gland; lung; spleen; trachea; stomach; adipose tissue; connective tissue; lymph; placenta; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p21.1
UniSTS entry: Chr 8 D8S1951
UniSTS entry: Chr 8 RH70272 [Map Viewer]
UniSTS entry: Chr 8 WI-20118 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

BT007396.1 Homo sapiens erythrocyte membrane protein band 4.9 (dematin) mRNA, complete cds P
BC052805.1 Homo sapiens erythrocyte membrane protein band 4.9 (dematin), mRNA (cDNA clone MGC:59859 IMAGE:6269658), complete cds PA
NM_001978.2 Homo sapiens erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 1, mRNA PA
AB209718.1 Homo sapiens premature mRNA for Dematin variant P
L19713.1 Human dematin (HRD1) mRNA, complete cds P
BC006318.2 Homo sapiens erythrocyte membrane protein band 4.9 (dematin), mRNA (cDNA clone MGC:12740 IMAGE:4125804), complete cds PA
BC017445.1 Homo sapiens erythrocyte membrane protein band 4.9 (dematin), mRNA (cDNA clone MGC:15601 IMAGE:3162732), complete cds PA
AK055842.1 Homo sapiens cDNA FLJ31280 fis, clone KIDNE2006687, highly similar to DEMATIN P
AK289650.1 Homo sapiens cDNA FLJ78462 complete cds, highly similar to Homo sapiens erythrocyte membrane protein band 4.9 (dematin), mRNA P
NM_001114139.1 Homo sapiens erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 6, mRNA PA
NM_001114138.1 Homo sapiens erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 5, mRNA PA
NM_001114137.1 Homo sapiens erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 4, mRNA PA
NM_001114136.1 Homo sapiens erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 3, mRNA PA
NM_001114135.2 Homo sapiens erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 2, mRNA PA
AK091581.1 Homo sapiens cDNA FLJ34262 fis, clone FEBRA2001814, highly similar to DEMATIN P
AK295452.1 Homo sapiens cDNA FLJ59528 complete cds, highly similar to Dematin P
U28389.1 Human dematin 52 kDa subunit mRNA, complete cds P

EST sequences (10 of 405) [Show all sequences]

AI022986.1 Clone IMAGE:1650912 parathyroid 3' read A
AI078235.1 Clone IMAGE:1675922 mixed 3' read PA
CB155425.1 Clone B2N807043-4-G05 brain 5' read
CB155426.1 Clone B2N807043-4-G06 brain 5' read
CB156378.1 Clone B2N807043-22-F08 brain 5' read P
CB155183.1 Clone B2N807043-13-B02 brain 5' read P
F30467.1 Clone s4000104B01 muscle
F36533.1 Clone sH5-000016-0/C04 muscle
Z20669.1 brain
AI866233.1 Clone IMAGE:2426157 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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