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UGID:143359     UniGene Hs.104741     Homo sapiens (human)   PBK
PDZ binding kinase (PBK)

Human protein-coding gene PBK. Represented by 314 ESTs from 98 cDNA libraries. EST representation biased toward infant. Corresponds to reference sequence NM_018492.2. [UniGene 143359 - Hs.104741]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_060962.2 PBK gene product H. sapiens 100.0 321
NP_001233441.1 PBK gene product P. troglodytes 99.7 321
NP_075698.1 lymphokine-activated killer T-cell-originated protein kinase M. musculus 89.4 320
NP_001088960.1 PDZ binding kinase X. laevis 77.0 321
NP_001002387.1 pbk gene product D. rerio 72.2 320
NP_573239.1 CG8173 D. melanogaster 46.9 177
Other hits (2 of 30) [Show all]SpeciesId(%)Len(aa)
XP_001109768.1 PREDICTED: lymphokine-activated killer T-cell-originated protein kinase isoform 1 M. mulatta 98.5 322
XP_003902639.1 PREDICTED: lymphokine-activated killer T-cell-originated protein kinase P. anubis 97.9 334

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: infant [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; liver; kidney; vascular; thymus; uncharacterized tissue; mixed; blood; embryonic tissue; placenta; skin; lymph node; lung; stomach; mammary gland; connective tissue; heart; esophagus; salivary gland; eye; muscle; ascites; uterus; bone; prostate; intestine; cervix; bone marrow; ovary
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p21.2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_018492.2 Homo sapiens PDZ binding kinase (PBK), mRNA PA
AB027249.1 Homo sapiens Nori-3 mRNA for MAPKK like protein kinase, complete cds PA
AB027250.1 Homo sapiens Nori-3 mRNA for MPAKK-like protein kinase cap site form 2, complete cds PA
AF189722.1 Homo sapiens PDZ-binding kinase mRNA, complete cds PA
AF237709.1 Homo sapiens spermatogenesis-related protein kinase mRNA, complete cds PA
AK027291.1 Homo sapiens cDNA FLJ14385 fis, clone HEMBA1002212, weakly similar to TYROSINE-PROTEIN KINASE 2 (EC 2.7.1.112) P
BC015191.1 Homo sapiens PDZ binding kinase, mRNA (cDNA clone MGC:14638 IMAGE:4082846), complete cds PA
AK301836.1 Homo sapiens cDNA FLJ58333 complete cds, highly similar to T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) P

EST sequences (10 of 314) [Show all sequences]

AA971676.1 Clone IMAGE:1583633 mixed 3' read A
AI002631.1 Clone IMAGE:1629113 mixed 3' read A
AI015407.1 Clone IMAGE:1618377 testis 3' read A
AI216689.1 Clone IMAGE:1840187 testis 3' read A
CB143138.1 Clone L16HLK3-29-C11 liver 5' read P
CB145325.1 Clone L16HLK3-19-G05 liver 5' read P
CB136759.1 Clone L5HLK1-42-H09 liver 5' read
CB114435.1 Clone L5HLK1s1-1-B04 liver 5' read P
CB124430.1 Clone L5HLK1s1-10-D08 liver 5' read P
CB125229.1 Clone L5HLK1s1-12-G12 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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