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UGID:142919     UniGene Hs.101337     Homo sapiens (human)   UCP3
Uncoupling protein 3 (mitochondrial, proton carrier) (UCP3)

Human protein-coding gene UCP3. Represented by 44 ESTs from 30 cDNA libraries. EST representation biased toward adult. Corresponds to 2 reference sequences (different isoforms). [UniGene 142919 - Hs.101337]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003347.1 UCP3 gene product H. sapiens 100.0 311
NP_033490.1 Ucp3 gene product M. musculus 85.7 307
NP_001080223.1 uncoupling protein 2 (mitochondrial, proton carrier) X. laevis 73.3 306
NP_571251.1 ucp2 gene product D. rerio 71.5 309
NP_190979.1 uncoupling mitochondrial protein 1 A. thaliana 48.1 295
XP_001695417.1 uncoupling protein C. reinhardtii 47.3 292
Other hits (2 of 46) [Show all]SpeciesId(%)Len(aa)
XP_001174875.1 PREDICTED: mitochondrial uncoupling protein 3 isoform 4 P. troglodytes 99.0 311
XP_001115599.1 PREDICTED: mitochondrial uncoupling protein 3 M. mulatta 96.5 311

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; muscle; lung; mammary gland; testis; heart; uterus; prostate; mouth; liver; blood; spinal cord; eye; mixed; connective tissue; brain; vascular; intestine; embryonic tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q13.4
UniSTS entry: UCP3
UniSTS entry: Chr 11 RH65723 [Map Viewer]
UniSTS entry: Chr 11 D11S2240E [Map Viewer]
UniSTS entry: Chr 11 D11S2239E [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_003356.3 Homo sapiens uncoupling protein 3 (mitochondrial, proton carrier) (UCP3), nuclear gene encoding mitochondrial protein, transcript variant long, mRNA PA
NM_022803.2 Homo sapiens uncoupling protein 3 (mitochondrial, proton carrier) (UCP3), nuclear gene encoding mitochondrial protein, transcript variant short, mRNA PA
BC008392.1 Homo sapiens uncoupling protein 3 (mitochondrial, proton carrier), mRNA (cDNA clone MGC:14479 IMAGE:4291158), complete cds PA
AK291889.1 Homo sapiens cDNA FLJ78613 complete cds, highly similar to Homo sapiens uncoupling protein 3 (mitochondrial, proton carrier) (UCP3), transcript variant short, mRNA P
AK290630.1 Homo sapiens cDNA FLJ77071 complete cds, highly similar to Homo sapiens uncoupling protein 3 (mitochondrial, proton carrier) (UCP3), transcript variant short, mRNA P
AK309873.1 Homo sapiens cDNA, FLJ99914 P
AK092685.1 Homo sapiens cDNA FLJ35366 fis, clone SKMUS2001215, highly similar to MITOCHONDRIAL UNCOUPLING PROTEIN 3 P
U82818.1 Homo sapiens UCP3S mRNA, complete cds PA
U84763.1 Homo sapiens UCP3 mRNA, complete cds P
AF001787.1 Homo sapiens uncoupling protein 3 mRNA, complete cds P
AF011449.1 Homo sapiens uncoupling protein-3 (UCP3) mRNA, nuclear gene encoding mitochondrial protein, complete cds P

EST sequences (10 of 44) [Show all sequences]

AI214734.1 Clone IMAGE:1840233 testis 3' read
AI632296.1 Clone IMAGE:2241514 uncharacterized tissue 3' read A
AI670961.1 Clone IMAGE:2305443 uncharacterized tissue 3' read A
Z28895.1 Clone B6C05 muscle
Z25295.1 Clone B6C05 muscle
Z28919.1 Clone C1A09 muscle
AI968020.1 Clone IMAGE:2516729 uncharacterized tissue 3' read A
AW295096.1 Clone IMAGE:2730345 uncharacterized tissue 3' read A
AW439483.1 Clone IMAGE:2778929 uterus 3' read A
CD616918.1 uncharacterized tissue P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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