2YIX: VAST+ Similar Structure Assemblies and Proteins

National Center for
Biotechnology Information

Triazolopyridine Inhibitors Of P38

Biological unit 1: monomeric

Source organism: Homo sapiens

Number of proteins:

1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)

Number of chemicals:

1 (1-ethyl-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo... ▼)

Chemical

Similar Structures (5330)

			PDB ID	Description	Taxonomy▲▼	Aligned Protein▲▼	RMSD▲▼	Aligned Residues▲▼	Sequence Identity▲▼
1	Expand row	Full	1ZZL	Crystal structure of P38 with triazolopyridine	Homo sapiens	1	0.33Å	351	100%
2	Expand row	Full	1W7H	p38 Kinase crystal structure in complex with small molecule inhibitor	Homo sapiens	1	1.09Å	351	100%
3	Expand row	Full	1WBW	Identification Of Novel P38 Alpha Map Kinase Inhibitors Using Fragment-Based Lead Generation	Homo sapiens	1	1.13Å	351	100%
4	Expand row	Full	1WBO	Fragment Based P38 Inhibitors	Homo sapiens	1	1.35Å	350	100%
5	Expand row	Full	2LGC	Joint NMR and X-ray refinement reveals the structure of a novel dibenzo[a,d]cycloheptenone inhibitor/p38 MAP kinase complex in solution	Homo sapiens	1	1.49Å	350	100%
6	Expand row	Full	3RIN	p38 kinase crystal structure in complex with small molecule inhibitor	Homo sapiens	1	0.83Å	349	100%
7	Expand row	Full	1OVE	The structure of p38 alpha in complex with a dihydroquinolinone	Homo sapiens	1	0.93Å	349	99%
8	Expand row	Full	3D7Z	Crystal Structure of P38 Kinase in Complex with a biphenyl amide inhibitor	Homo sapiens	1	0.99Å	349	99%
9	Expand row	Full	1BL6	THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB216995	Homo sapiens	1	0.99Å	349	100%
10	Expand row	Full	1BMK	THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB218655	Homo sapiens	1	1.04Å	349	99%

{"1":"MITOGEN-ACTIVATED PROTEIN KINASE 14"}