3MZS: VAST+ Similar Structure Assemblies and Proteins

National Center for
Biotechnology Information

Crystal Structure of Cytochrome P450 CYP11A1 in complex with 22-hydroxy-cholesterol

Biological unit 1: monomeric

Source organism: Bos taurus

Number of proteins:

1 (Cholesterol side-chain cleavage enzyme)

Number of chemicals:

3 ((3alpha,8alpha,22R)-cholest-5-ene-3,22-diol,PRO... ▼)

Chemical

	(3alpha,8alpha,22R)-cholest-5-ene-3,22-diol
	PROTOPORPHYRIN IX CONTAINING FE
	ISOPROPYL ALCOHOL

Similar Structures (973)

			PDB ID	Description	Taxonomy▲▼	Aligned Protein▲▼	RMSD▲▼	Aligned Residues▲▼	Sequence Identity▲▼
1	Expand row	Full	3NA1	Crystal structure of human CYP11A1 in complex with 20-hydroxycholesterol	Homo sapiens	1	1.14Å	470	74%
2	Expand row	Full	3N9Y	Crystal structure of human CYP11A1 in complex with cholesterol	Homo sapiens	1	1.11Å	469	74%
3	Expand row	Full	3NA0	Crystal structure of human CYP11A1 in complex with 20,22-dihydroxycholesterol	Homo sapiens	1	1.05Å	467	74%
4	Expand row	Full	3N9Z	Crystal structure of human CYP11A1 in complex with 22-hydroxycholesterol	Homo sapiens	1	1.05Å	467	74%
5	Expand row	Full	6XZ8	Structure of aldosterone synthase (CYP11B2) in complex with N-[(1R)-1-[5-(6-chloro-1,1-dimethyl-3-oxo-isoindolin-2-yl)-3-pyridyl]ethyl]methanesulfonamide	Homo sapiens	1	2.18Å	462	37%
6	Expand row	Full	3K9V	Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CHAPS	Rattus norvegicus	1	3.31Å	462	28%
7	Expand row	Full	4FDH	Structure of human aldosterone synthase, CYP11B2, in complex with fadrozole	Homo sapiens	1	2.20Å	461	37%
8	Expand row	Full	6XZ9	Structure of aldosterone synthase (CYP11B2) in complex with 5-chloro-3,3-dimethyl-2-[5-[1-(1-methylpyrazole-4-carbonyl)azetidin-3-yl]oxy-3-pyridyl]isoindolin-1-one	Homo sapiens	1	2.21Å	461	37%
9	Expand row	Full	6M7X	Structure of human CYP11B1 in complex with fadrozole	Homo sapiens	1	2.39Å	461	37%
10	Expand row	Full	4DVQ	Structure of human aldosterone synthase, CYP11B2, in complex with deoxycorticosterone	Homo sapiens	1	2.20Å	460	38%

{"1":"Cholesterol side-chain cleavage enzyme"}