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1KXU: 
CYCLIN H, A POSITIVE REGULATORY SUBUNIT OF CDK ACTIVATING KINASE
Biological unit 1: dimeric
Source organism: Homo sapiens
Number of proteins:
2 (CYCLIN H ▼)
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 CYCLIN H
Similar Structures (159)help
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Showing 1 to 10 out of 159 selected structures help
      PDB ID Description Taxonomy▲▼ Aligned Protein▲▼ RMSD▲▼ Aligned Residues▲▼ Sequence Identity▲▼
1
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Full
 1JKW
STRUCTURE OF CYCLIN MCS2
Homo sapiens
 2 0.93Å 548 99%
2
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Full
 2PK2
Cyclin box structure of the P-TEFb subunit Cyclin T1 derived from a fusion complex with EIAV Tat
Others
 2 3.87Å 424 17%
3
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Partial
 5HVY
CDK8/CYCC IN COMPLEX WITH COMPOUND 20
Homo sapiens
 1 2.98Å 231 25%
4
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Partial
 4F7J
Crystal structure of human CDK8/CYCC in complex with compound 3 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(2-hydroxyethyl)urea)
Homo sapiens
 1 2.98Å 231 25%
5
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Partial
 6QTJ
Crystal structure of human CDK8/CYCC in complex with BI 919811
Homo sapiens
 1 2.77Å 229 26%
6
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Partial
 5I5Z
CDK8-CYCC IN COMPLEX WITH 8-(1-Methyl-2,2-dioxo-2,3-dihydro-1H-2l6-benzo[c]isothiazol-5-yl)-[1,6]naphthyridine-2-carboxylic acid methylamide
Homo sapiens
 1 2.86Å 229 25%
7
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Partial
 4F70
Crystal structure of human CDK8/CYCC in complex with compound 4 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[2-(morpholin-4-yl)ethyl]urea)
Homo sapiens
 1 2.89Å 229 26%
8
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Partial
 5XS2
CDK8-CYCC IN COMPLEX WITH COMPOUND 17:3-chloro-4-(4-pyridyl)-1H-pyrrole-2-carboxamide
Homo sapiens
 1 2.90Å 229 25%
9
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Partial
 3RGF
Crystal Structure of human CDK8/CycC
Homo sapiens
 1 2.90Å 229 25%
10
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Partial
 4F6W
Crystal structure of human CDK8/CYCC in complex with compound 1 (N-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-4-[2-({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]carbamoyl}amino)ethyl]piperazine-1-carboxamide)
Homo sapiens
 1 2.91Å 229 26%
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{"1":"CYCLIN H","140":"CYCLIN H"}
Citing VAST
Gibrat JF, Madej T, Bryant SH. "Surprising similarities in structure comparison.", Curr Opin Struct Biol.1996 Jun;6(3):377-85
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. "MMDB and VAST+: tracking structural similarities between macromolecular complexes." Nucl. Acids Res. 2014 Jan;42(Database issue):D297-303
Thomas Madej, Aron Marchler-Bauer, Christopher Lanczycki, Dachuan Zhang, Stephen H Bryant "Biological Assembly Comparison With VAST" Methods Mol. Biol. 2020(2112):175-186
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?Original VAST
Original VAST finds structures that are similar to individual protein molecules, or individual 3D domains, in your query structure. Select a protein molecule ("chain") or 3D domain of interest from the table below to view a list of other proteins or domains that have a similar 3D shape. In contrast to VAST+, which focuses on the default biological unit, Original VAST lists all protein molecules in the asymmetric unit of the query structure.