1Y57: VAST+ Similar Structure Assemblies and Proteins

National Center for
Biotechnology Information

Structure of unphosphorylated c-Src in complex with an inhibitor

Biological unit 1: monomeric

Source organism: Homo sapiens

Number of proteins:

1 (Proto-oncogene tyrosine-protein kinase Src)

Number of chemicals:

6 (4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-N-{3-[(4-PYR... ▼)

Chemical

	4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-N-{3-[(4-PYRIDIN-3-YLPYRIMIDIN-2-YL)AMINO]PHENYL}BENZAMIDE
	SULFATE ION (5)

Similar Structures (5674)

			PDB ID	Description	Taxonomy▲▼	Aligned Protein▲▼	RMSD▲▼	Aligned Residues▲▼	Sequence Identity▲▼
1	Expand row	Full	3KXX	Structure of the mutant Fibroblast Growth Factor receptor 1	Homo sapiens	1	2.22Å	275	37%
2	Expand row	Full	6FHB	Death-associated Protein Kinase 1 (DAPK1) catalytic and auto-regulatory domains with S289A and S308E mutations	Homo sapiens	1	3.05Å	274	21%
3	Expand row	Full	2CKE	Human death-associated DRP-1 kinase in complex with inhibitor	Homo sapiens	1	3.17Å	274	21%
4	Expand row	Full	2XUU	Crystal structure of a DAP-kinase 1 mutant	Homo sapiens	1	2.98Å	273	21%
5	Expand row	Full	2A27	Human DRP-1 kinase, W305S S308A D40 mutant, crystal form with 8 monomers in the asymmetric unit	Homo sapiens	1	3.00Å	273	22%
6	Expand row	Full	2W4K	X-ray structure of a DAP-Kinase 2-302	Homo sapiens	1	3.02Å	273	21%
7	Expand row	Full	2YAA	Crystal structure of the autoinhibited form of mouse DAPK2 in complex with ATP	Mus musculus	1	2.95Å	272	22%
8	Expand row	Full	2YA9	Crystal structure of the autoinhibited form of mouse DAPK2	Mus musculus	1	3.03Å	272	22%
9	Expand row	Full	1WMK	Human death-associated kinase DRP-1, mutant S308D d40	Homo sapiens	1	3.03Å	272	22%
10	Expand row	Full	1Z9X	Human DRP-1 kinase, W305S S308A D40 mutant, crystal form with 3 monomers in the asymmetric unit	Homo sapiens	1	3.09Å	272	22%

{"1":"Proto-oncogene tyrosine-protein kinase Src"}