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1LDK: 
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex
Biological unit 1: pentameric
Source organism: Homo sapiens
Number of proteins:
5 (CULLIN HOMOLOG, CYCLIN A/CDK2-ASSOCIATED PROTEI... ▼)
Protein molecule
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AA -Click to explore this molecule neighbors
 CULLIN HOMOLOG
BB -Click to explore this molecule neighbors
 CULLIN HOMOLOG
CC -Click to explore this molecule neighbors
 ring-box protein 1
DD -Click to explore this molecule neighbors
 CYCLIN A/CDK2-ASSOCIATED PROTEIN P19
EE -Click to explore this molecule neighbors
 SKP2-like protein type gamma
Number of chemicals:
3 (ZINC ION (3) ▼)
Chemical
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ZINC ION (3)
Similar Structures (356)help
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Showing 1 to 10 out of 356 selected structures help
      PDB ID Description Taxonomy▲▼ Aligned Protein▲▼ RMSD▲▼ Aligned Residues▲▼ Sequence Identity▲▼
1
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Partial
 6TTU
Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2
Homo sapiens
 2 1.67Å 466 100%
2
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Partial
 5NLB
Crystal structure of human CUL3 N-terminal domain bound to KEAP1 BTB and 3-box
Homo sapiens
 2 3.41Å 427 25%
3
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Partial
 6R7F
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Homo sapiens
 2 2.70Å 426 31%
4
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Partial
 6R7H
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Homo sapiens
 2 3.13Å 424 31%
5
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Partial
 6R6H
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Homo sapiens
 2 3.49Å 424 28%
6
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Partial
 4AP2
Crystal structure of the human KLHL11-Cul3 complex at 2.8A resolution
Homo sapiens
 2 3.65Å 423 27%
7
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Partial
 4JGH
Structure of the SOCS2-Elongin BC complex bound to an N-terminal fragment of Cullin5
Homo sapiens/Mus musculus
 2 3.98Å 419 29%
8
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Partial
 6I2M
Crystal structure of vaccinia virus protein A55 BTB-Back domain in complex with human Cullin-3 N-terminus
Others
 2 4.18Å 419 25%
9
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Partial
 4HXI
Crystal structure of KLHL3/Cul3 complex
Homo sapiens
 2 3.72Å 418 26%
10
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Partial
 6R7I
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Homo sapiens
 2 4.59Å 417 19%
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{"1":"CULLIN HOMOLOG","2":"CULLIN HOMOLOG","3":"ring-box protein 1","4":"CYCLIN A/CDK2-ASSOCIATED PROTEIN P19","5":"SKP2-like protein type gamma"}
Citing VAST
Gibrat JF, Madej T, Bryant SH. "Surprising similarities in structure comparison.", Curr Opin Struct Biol.1996 Jun;6(3):377-85
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. "MMDB and VAST+: tracking structural similarities between macromolecular complexes." Nucl. Acids Res. 2014 Jan;42(Database issue):D297-303
Thomas Madej, Aron Marchler-Bauer, Christopher Lanczycki, Dachuan Zhang, Stephen H Bryant "Biological Assembly Comparison With VAST" Methods Mol. Biol. 2020(2112):175-186
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?Original VAST
Original VAST finds structures that are similar to individual protein molecules, or individual 3D domains, in your query structure. Select a protein molecule ("chain") or 3D domain of interest from the table below to view a list of other proteins or domains that have a similar 3D shape. In contrast to VAST+, which focuses on the default biological unit, Original VAST lists all protein molecules in the asymmetric unit of the query structure.