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serpin B7

serpin family B member 7 (serpin B7, also called megsin) is primarily expressed in the mesangium, and is thought to play a role in the regulation of a wide variety of processes in mesangial cells, such as matrix metabolism, cell proliferation, and apoptosis

Arch. IDVersionDate PublishedReview Level
1444440612021-11-30
curated
Arch. ID14444406
Version1
Date Published2021-11-30
Review Level
curated
serpinB7_megsin: serpin family B member 7, megsinserpinB7_megsin
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Sequences with this architecture
Name, label and taxonomic scope
Taxonomic scopeNameLabel
All organismsserpin B7serpin family B member 7 (serpin B7, also called megsin) is primarily expressed in the mesangium, and is thought to play a role in the regulation of a wide variety of processes in mesangial cells, such as matrix metabolism, cell proliferation, and apoptosis
Name, label and taxonomic scope
Tax. ExpAll organisms
Nameserpin B7
Labelserpin family B member 7 (serpin B7, also called megsin) is primarily expressed in the mesangium, and is thought to play a role in the regulation of a wide variety of processes in mesangial cells, such as matrix metabolism, cell proliferation, and apoptosis
Supporting evidence
CDD
  • cd19566: serpinB7_megsin : serpin family B member 7, megsin
Protein Accession
  • O75635: RecName: Full=Serpin B7; AltName: Full=Megsin; AltName: Full=TP55
  • NP_081824: serpin B7 [Mus musculus]
  • AAL16768: megsin [Mus musculus]
Gene IDs
Publications
  • PMID 24207119: Mutations in SERPINB7, encoding a member of the serine protease inhibitor superfamily, cause Nagashima-type palmoplantar keratosis.
  • PMID 9182567: Purification, cDNA cloning, and characterization of a new serpin with megakaryocyte maturation activity.
Conserved domains in this architecture
AccessionShort nameTitle
cd19566serpinB7_megsinserpin family B member 7, megsin
Functional sites in this architecture
TitleTypeSource domain
reactive center loop (RCL)othercd19566

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