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DEAD/DEAH box helicase

DEAD/DEAH box containing ATP-dependent helicase catalyzes the unwinding of DNA or RNA

Arch. IDVersionDate PublishedReview Level
1302917122024-05-29
curated
Arch. ID13029171
Version2
Date Published2024-05-29
Review Level
curated
DEXDc_SHPRH-like: DEXH-box helicase domain of SHPRH-like proteinsDEXDc_SHPRH-likeSF2_C_SNF: C-terminal helicase domain of the SNF family helicasesSF2_C_SNF
EC:  3.6.4.-
Gene Ontology:  GO:0016887 | GO:0003676 | GO:0004386 | GO:0005524
PubMed:  20206133 | 20225155
CATH:  3.40.50.300
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Sequences with this architecture
Name, label and taxonomic scope
Taxonomic scopeNameLabel
All organismsDEAD/DEAH box helicaseDEAD/DEAH box containing ATP-dependent helicase catalyzes the unwinding of DNA or RNA
Name, label and taxonomic scope
Tax. ExpAll organisms
NameDEAD/DEAH box helicase
LabelDEAD/DEAH box containing ATP-dependent helicase catalyzes the unwinding of DNA or RNA
Supporting evidence
E.C. Number
CDD
  • cd18008: DEXDc_SHPRH-like : DEXH-box helicase domain of SHPRH-like proteins
  • cd18793: SF2_C_SNF : C-terminal helicase domain of the SNF family helicases
Protein Accession
  • OAQ73751: SNF2 family helicase/ATPase [Pochonia chlamydosporia 170]
Gene IDs
Publications
  • PMID 20206133: DEAD-box helicases: posttranslational regulation and function.
  • PMID 21779027: From unwinding to clamping - the DEAD box RNA helicase family.
  • PMID 20225155: Duplex unwinding with DEAD-box proteins.
Conserved domains in this architecture
AccessionShort nameTitle
cd18008DEXDc_SHPRH-likeDEXH-box helicase domain of SHPRH-like proteins
cd18793SF2_C_SNFC-terminal helicase domain of the SNF family helicases
Functional sites in this architecture
TitleTypeSource domain
ATP binding sitechemical bindingcd18008
DEAD box helicase motifothercd18008
ATP binding sitechemical bindingcd18793
DNA binding sitenucleotide bindingcd18793

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