type I polyketide synthase
type I polyketide synthase assembles complex polyketides via the head-to-tail fusion of acyl and malonyl building blocks
Arch. ID | Version | Date Published | Review Level |
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12220529 | 2 | 2022-03-11 | curated |
Arch. ID | 12220529 |
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Version | 2 |
Date Published | 2022-03-11 |
Review Level | curated |
Sequences with this architecture |
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Supporting evidence | |
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CDD |
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Protein Accession |
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Conserved domains in this architecture | ||
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Accession | Short name | Title |
COG3321 | PksD | Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism] |
cd08952 | KR_1_SDR_x | ketoreductase (KR), subgroup 1, complex (x) SDRs |
cd08956 | KR_3_FAS_SDR_x | beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 3, complex (x) |
smart00823 | PKS_PP | Phosphopantetheine attachment site |
smart00827 | PKS_AT | Acyl transferase domain in polyketide synthase (PKS) enzymes |
Functional sites in this architecture | ||
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Title | Type | Source domain |
active site | active | cd08952 |
NADP binding site | chemical binding | cd08952 |
active site | active | cd08956 |
putative NADP binding site | chemical binding | cd08956 |