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DEAD/DEAH box helicase

DEAD/DEAH box containing ATP-dependent helicase catalyzes the unwinding of DNA or RNA

Arch. IDVersionDate PublishedReview Level
1143733272024-05-24
curated
Arch. ID11437332
Version7
Date Published2024-05-24
Review Level
curated
SSL2: Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]SSL2
EC:  3.6.4.-
Gene Ontology:  GO:0016887 | GO:0003676 | GO:0004386 | GO:0005524
PubMed:  20206133 | 20225155
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Sequences with this architecture
Name, label and taxonomic scope
Taxonomic scopeNameLabel
All organismsDEAD/DEAH box helicaseDEAD/DEAH box containing ATP-dependent helicase catalyzes the unwinding of DNA or RNA
Name, label and taxonomic scope
Tax. ExpAll organisms
NameDEAD/DEAH box helicase
LabelDEAD/DEAH box containing ATP-dependent helicase catalyzes the unwinding of DNA or RNA
Supporting evidence
E.C. Number
CDD
  • COG1061: SSL2 : Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]
Protein Accession
  • Q1MTR1: RecName: Full=Putative mitochondrial ATP-dependent helicase irc3
  • Q9J550: RecName: Full=Transcript termination protein A18
Publications
  • PMID 31035307: Crystal structure of a novel ATPase RadD from Escherichia coli.
  • PMID 20206133: DEAD-box helicases: posttranslational regulation and function.
  • PMID 21779027: From unwinding to clamping - the DEAD box RNA helicase family.
  • PMID 20225155: Duplex unwinding with DEAD-box proteins.
3-D Structures
  • 5TNUS. tokodaii XPB II crystal structure at 3.0 Angstrom resolution
  • 6JDEcrystal structure of a DNA repair protein

5TNU

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refnum,11,12,,21,22,,10C,11C,20C
1TUP_A,100,101,,,132,,,,
1TUP_B,110,111,,141,142,,,,
1TUP_C,,,,,,,200,201,230
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Annotations: 
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Conserved domains in this architecture
AccessionShort nameTitle
COG1061SSL2Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]

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