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chemotaxis protein CheA

two-component sensor histidine kinase containing a CheA regulatory domain, may function in chemotaxis by relaying sensory signals from chemoreceptors to flagellar motors

Arch. IDVersionDate PublishedReview Level
1081521312016-09-27
curated
Arch. ID10815213
Version1
Date Published2016-09-27
Review Level
curated
HPT: Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator proteinHPTHc1: Histone H1-like protein Hc1Hc1H-kinase_dim: Signal transducing histidine kinase, homodimeric domainH-kinase_dimHATPase_c: Histidine kinase-like ATPasesHATPase_cCheA_reg: CheA regulatory domainCheA_reg
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Sequences with this architecture
This architecture currently does not link to any protein sequence records.
Name, label and taxonomic scope
Taxonomic scopeNameLabel
All organismschemotaxis protein CheAtwo-component sensor histidine kinase containing a CheA regulatory domain, may function in chemotaxis by relaying sensory signals from chemoreceptors to flagellar motors
Name, label and taxonomic scope
Tax. ExpAll organisms
Namechemotaxis protein CheA
Labeltwo-component sensor histidine kinase containing a CheA regulatory domain, may function in chemotaxis by relaying sensory signals from chemoreceptors to flagellar motors
Supporting evidence
Comments
  • contains homodimer domain of signal transducing histidine kinase, and an N-terminal histidine phosphotransfer (HpT) domain
Protein Accession
  • Q53135: Chemotaxis protein CheA
  • Q52880: Chemotaxis protein CheA
  • AAF32417: chemotaxis protein CheA [Vibrio parahaemolyticus]
  • KYX72653: chemotaxis protein CheA [Vibrio parahaemolyticus]
Publications
  • PMID 7494484: Identification of a chemotaxis operon with two cheY genes in Rhodobacter sphaeroides.
  • PMID 7860605: Isolation and characterization of chemotaxis mutants and genes of Pseudomonas aeruginosa.
  • PMID 10648530: Insertional inactivation of genes encoding components of the sodium-type flagellar motor and switch of Vibrio parahaemolyticus.
CDD
  • smart00387: HATPase_c : Histidine kinase-like ATPases
  • pfam02895: H-kinase_dim : Signal transducing histidine kinase, homodimeric domain
  • cd00088: HPT : Histidine Phosphotransfer domain, involved in signalling through a two part component...
  • cd00731: CheA_reg : CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and...
Conserved domains in this architecture
AccessionShort nameTitle
cd00088HPTHistidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein
cd00731CheA_regCheA regulatory domain
cl22514Hc1Histone H1-like protein Hc1
pfam02895H-kinase_dimSignal transducing histidine kinase, homodimeric domain
smart00387HATPase_cHistidine kinase-like ATPases
Functional sites in this architecture
TitleTypeSource domain
active siteactivecd00088
putative binding surfaceactivecd00088

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