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acyltransferase

acyltransferase belonging to the transferase hexapeptide repeat family, catalyzes the transfer of an acyl group from an acyl-CoA to a substrate; similar to O-antigen biosynthesis protein WlbB, a bacterial N-acetyltransferase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid

Arch. IDVersionDate PublishedReview Level
1021356142022-08-24
curated
Arch. ID10213561
Version4
Date Published2022-08-24
Review Level
curated
LbetaH: Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X)LbetaHLbH_WxcM_N_like: WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domainLbH_WxcM_N_like
EC:  2.3.1.-
CATH:  2.160.10.10
Gene Ontology:  GO:0016746 | GO:0120225
PubMed:  15500694
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Sequences with this architecture
Name, label and taxonomic scope
Taxonomic scopeNameLabel
All organismsacyltransferaseacyltransferase belonging to the transferase hexapeptide repeat family, catalyzes the transfer of an acyl group from an acyl-CoA to a substrate; similar to O-antigen biosynthesis protein WlbB, a bacterial N-acetyltransferase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid
Name, label and taxonomic scope
Tax. ExpAll organisms
Nameacyltransferase
Labelacyltransferase belonging to the transferase hexapeptide repeat family, catalyzes the transfer of an acyl group from an acyl-CoA to a substrate; similar to O-antigen biosynthesis protein WlbB, a bacterial N-acetyltransferase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid
Supporting evidence
E.C. Number
Publications
  • PMID 20433200: Molecular structure of WlbB, a bacterial N-acetyltransferase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid .
  • PMID 15500694: The structurally constrained protein evolution model accounts for sequence patterns of the LbetaH superfamily.
CDD
  • cd03358: LbH_WxcM_N_like : WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is...
Conserved domains in this architecture
AccessionShort nameTitle
cd03358LbH_WxcM_N_likeWcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain
cl00160LbetaHLeft-handed parallel beta-Helix (LbetaH or LbH) domain
Functional sites in this architecture
TitleTypeSource domain
putative active siteactivecd03358
putative CoA binding sitechemical bindingcd03358
putative substrate binding sitechemical bindingcd03358
putative trimer interfacepolypeptide bindingcd03358

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