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AdoMetDC family protein

AdoMetDC family protein similar to S-adenosylmethionine decarboxylase that catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet)and its paralog, arginine decarboxylase that catalyzes the decarboxylation of L-arginine to agmatine

Arch. IDVersionDate PublishedReview Level
1001144822019-10-09
curated
Arch. ID10011448
Version2
Date Published2019-10-09
Review Level
curated
Obsolete: This domain/cluster is obsoleteObsolete
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Sequences with this architecture
This architecture currently does not link to any protein sequence records.
Name, label and taxonomic scope
Taxonomic scopeNameLabel
All organismsAdoMetDC family proteinAdoMetDC family protein similar to S-adenosylmethionine decarboxylase that catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet)and its paralog, arginine decarboxylase that catalyzes the decarboxylation of L-arginine to agmatine
Name, label and taxonomic scope
Tax. ExpAll organisms
NameAdoMetDC family protein
LabelAdoMetDC family protein similar to S-adenosylmethionine decarboxylase that catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet)and its paralog, arginine decarboxylase that catalyzes the decarboxylation of L-arginine to agmatine
Supporting evidence
Comments
  • S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine
  • S-adenosylmethionine decarboxylase, is also known as AdoMetDC; SAMDC; S-adenosylmethionine decarboxylase proenzyme; S-adenosyl-L-methionine carboxy-lyase; S-adenosyl-L-methionine decarboxylase.
  • arginine decarboxylase is also known as ADC; ArgDC; pyruvoyl-dependent arginine decarboxylase.
E.C. Number
Protein Accession
  • Q9UWY8: RecName: Full=S-adenosylmethionine decarboxylase proenzyme; Short=AdoMetDC; Short=SAMDC; Contains: RecName: Full=S-adenosylmethionine decarboxylase beta chain; Contains: RecName: Full=S-adenosylmethionine decarboxylase alpha chain; Flags: Precursor
  • Q9UWU1: RecName: Full=Arginine decarboxylase proenzyme; Short=ADC; Short=ArgDC; AltName: Full=Pyruvoyl-dependent arginine decarboxylase; Contains: RecName: Full=Arginine decarboxylase beta chain; Contains: RecName: Full=Arginine decarboxylase alpha chain; Flags:
CDD
  • PRK00458: S-adenosylmethionine decarboxylase proenzyme; Provisional
  • COG1586: SpeD : S-adenosylmethionine decarboxylase or arginine decarboxylase [Amino acid transport and metabolism]
  • pfam02675: AdoMet_dc : S-adenosylmethionine decarboxylase
  • TIGR03330: SAM_DCase_Bsu : S-adenosylmethionine decarboxylase proenzyme, Bacillus form
Publications
  • PMID 18650422: Crenarchaeal arginine decarboxylase evolved from an S-adenosylmethionine decarboxylase enzyme.
  • PMID 1649051: S-adenosylmethionine decarboxylase from the thermophilic archaebacterium Sulfolobus solfataricus. Purification, molecular properties and studies on the covalently bound pyruvate.
Conserved domains in this architecture
AccessionShort nameTitle
PRK00458ObsoleteThis domain/cluster is obsolete

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