9IVG: Cryo-EM structure of the GLP-1(9-36)-bound human GLP-1R-Gs complex

PDB ID: 9IVGDownload
MMDB ID: 255859
PDB Deposition Date: 2024/7/23
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
Similar Structures:
Molecular Components in 9IVG
Label Count Molecule
Proteins (6 molecules)
1
Glp-1(9-36)
Molecule annotation
1
Glucagon-like Peptide 1 Receptor
(Gene symbol: GLP1R)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1,guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
(Gene symbol: GNAS)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
1
Nanobody-35
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303