9FAZ: Gcase in complex with small molecule inhibitor 1

PDB ID: 9FAZDownload
MMDB ID: 249385
PDB Deposition Date: 2024/5/10
Updated in MMDB: 2024/07
Experimental Method:
x-ray diffraction
Resolution: 1.63  Å
Source Organism:
Similar Structures:
Biological Unit for 9FAZ: monomeric; determined by author
Molecular Components in 9FAZ
Label Count Molecule
Protein (1 molecule)
1
Lysosomal Acid Glucosylceramidase
(Gene symbol: GBA)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
5
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
POTASSIUM IONPOTASSIUM ION
3
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
6
1
SULFATE IONSULFATE ION
7
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303