9EWS: Optimisation of Potent, Efficacious, Selective and Blood-Brain Barrier Penetrating Inhibitors Targeting EGFR Exon20 Insertion Mutations

PDB ID: 9EWSDownload
MMDB ID: 254761
PDB Deposition Date: 2024/4/4
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.435  Å
Source Organism:
Similar Structures:
Biological Unit for 9EWS: monomeric; determined by author
Molecular Components in 9EWS
Label Count Molecule
Protein (1 molecule)
1
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
1
Unknown
2
15
IODIDE IONIODIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303