9EMV: SARS-CoV-2 nsp10-16 methyltransferase in complex with Sangivamycin and m7GpppA (Cap0-analog)/m7GpppAm (Cap1-analog)

PDB ID: 9EMVDownload
MMDB ID: 244432
PDB Deposition Date: 2024/3/11
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.34  Å
Source Organism:
Similar Structures:
Biological Unit for 9EMV: dimeric; determined by author and by software (PISA)
Molecular Components in 9EMV
Label Count Molecule
Proteins (2 molecules)
1
2'-o-methyltransferase Nsp16
Molecule annotation
1
Non-structural Protein 10
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
1
SANGIVAMYCINSANGIVAMYCIN
2
1
P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATEP1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE
3
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
4
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
5
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
1
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE
7
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303