9DTR: Structure of the yeast post-catalytic P complex spliceosome at 2.3 Angstrom resolution

PDB ID: 9DTRDownload
MMDB ID: 257317
PDB Deposition Date: 2024/10/1
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 2.31  Å
Source Organism:
Similar Structures:
Biological Unit for 9DTR: 47-meric; determined by author and by software
Molecular Components in 9DTR
Label Count Molecule
Proteins (42 molecules)
1
Pre-mrna-splicing Factor 8
(Gene symbol: PRP8)
Molecule annotation
1
Pre-mrna-splicing Factor Snu114
(Gene symbol: SNU114)
Molecule annotation
1
Protein Fyv6
(Gene symbol: FYV6)
Molecule annotation
1
Pre-mrna-splicing Factor Isy1
(Gene symbol: ISY1)
Molecule annotation
1
Pre-mrna-splicing Factor Cwc22
(Gene symbol: CWC22)
Molecule annotation
1
Pre-mrna-splicing Factor Prp46
(Gene symbol: PRP46)
Molecule annotation
1
Pre-mrna-processing Protein 45
(Gene symbol: PRP45)
Molecule annotation
1
Pre-mrna-splicing Factor Bud31
(Gene symbol: BUD31)
Molecule annotation
1
Pre-mrna-splicing Factor Cwc2
(Gene symbol: CWC2)
Molecule annotation
1
Pre-mrna-splicing Factor Slt11
(Gene symbol: ECM2)
Molecule annotation
1
Pre-mrna-splicing Factor Cef1
(Gene symbol: CEF1)
Molecule annotation
1
Pre-mrna-splicing Factor Cwc15
(Gene symbol: CWC15)
Molecule annotation
1
Pre-mrna-splicing Factor Cwc21
(Gene symbol: CWC21)
Molecule annotation
1
Pre-mrna-splicing Factor Clf1
(Gene symbol: CLF1)
Molecule annotation
1
Pre-mrna-splicing Factor Syf1
(Gene symbol: SYF1)
Molecule annotation
1
Pre-mrna-splicing Factor Atp-dependent RNA Helicase Prp22
(Gene symbol: PRP22)
Molecule annotation
1
U2 Small Nuclear Ribonucleoprotein A'
(Gene symbol: LEA1)
Molecule annotation
1
U2 Small Nuclear Ribonucleoprotein B''
(Gene symbol: MSL1)
Molecule annotation
1
Pre-mrna-splicing Factor Ntc20
(Gene symbol: NTC20)
Molecule annotation
1
Pre-mrna-splicing Factor 18
(Gene symbol: PRP18)
Molecule annotation
2
Small Nuclear Ribonucleoprotein-associated Protein B
(Gene symbol: SMB1)
Molecule annotation
1
Pre-mrna-splicing Factor Slu7
(Gene symbol: SLU7)
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D3
(Gene symbol: SMD3)
Molecule annotation
2
Small Nuclear Ribonucleoprotein E
(Gene symbol: SME1)
Molecule annotation
2
Small Nuclear Ribonucleoprotein F
(Gene symbol: SMX3)
Molecule annotation
2
Small Nuclear Ribonucleoprotein G
(Gene symbol: SMX2)
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D1
(Gene symbol: SMD1)
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D2
(Gene symbol: SMD2)
Molecule annotation
1
Pre-mrna-processing Factor 17
(Gene symbol: CDC40)
Molecule annotation
1
Pre-mrna-splicing Factor Snt309
(Gene symbol: SNT309)
Molecule annotation
4
Pre-mrna-processing Factor 19
(Gene symbol: PRP19)
Molecule annotation
1
Pre-mrna-splicing Factor Syf2
(Gene symbol: SYF2)
Molecule annotation
Nucleotides(5 molecules)
1
U2 Snrna
Molecule annotation
1
U5 Snrna
Molecule annotation
1
U6 Snrna
Molecule annotation
1
Ubc4 mRNA Spliced Exons
Molecule annotation
1
Ubc4 Lariat-intron
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
4
POTASSIUM IONPOTASSIUM ION
3
2
INOSITOL HEXAKISPHOSPHATEINOSITOL HEXAKISPHOSPHATE
4
1
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
5
7
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303