9CI9: Crystal structure of human polymerase eta with incoming dCMPnPP nucleotide across threofuranosyl thymidine in DNA template at extension stage

PDB ID: 9CI9Download
MMDB ID: 252559
PDB Deposition Date: 2024/7/2
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.09  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 9CI9: trimeric; determined by author and by software (PISA)
Molecular Components in 9CI9
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase ETA
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*cp*ap*tp*gp*(tft)p*tp*gp*ap*cp*gp*cp*t)-3')
Molecule annotation
1
DNA (5'-d(*ap*gp*cp*gp*tp*cp*ap*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine
2
2
MAGNESIUM IONMAGNESIUM ION
3
3
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303