9CBM: Cryo-EM structure of dexmedetomidine-bound alpha-2A-adrenergic receptor in complex with heterotrimeric Gi-protein

PDB ID: 9CBMDownload
MMDB ID: 252295
PDB Deposition Date: 2024/6/19
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 9CBM: tetrameric; determined by author and by software
Molecular Components in 9CBM
Label Count Molecule
Proteins (4 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Endolysin,alpha-2a Adrenergic Receptor
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-[(1~{S})-1-(2,3-dimethylphenyl)ethyl]-1~{H}-imidazole4-[(1~{S})-1-(2,3-dimethylphenyl)ethyl]-1~{H}-imidazole
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303