9CAQ: Cryo-EM structure of a human MCM2-7 double hexamer formed from independently loaded MCM2-7 single hexamers

PDB ID: 9CAQDownload
MMDB ID: 253106
PDB Deposition Date: 2024/6/17
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 9CAQ: 14-meric; determined by author
Molecular Components in 9CAQ
Label Count Molecule
Proteins (12 molecules)
2
DNA Replication Licensing Factor Mcm2
Molecule annotation
2
DNA Replication Licensing Factor Mcm3
Molecule annotation
2
DNA Replication Licensing Factor Mcm4
Molecule annotation
2
DNA Replication Licensing Factor Mcm5
Molecule annotation
2
DNA Replication Licensing Factor Mcm6
Molecule annotation
2
DNA Replication Licensing Factor Mcm7
Molecule annotation
Nucleotides(2 molecules)
1
DNA (44-mer)
Molecule annotation
1
DNA (44-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (29 molecules)
1
10
ZINC IONZINC ION
2
9
MAGNESIUM IONMAGNESIUM ION
3
2
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
4
8
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303