9C9M: HIV-1 intasome core bound with DTG

PDB ID: 9C9MDownload
MMDB ID: 250536
PDB Deposition Date: 2024/6/14
Updated in MMDB: 2024/08
Experimental Method:
electron microscopy
Resolution: 2.01  Å
Source Organism:
Similar Structures:
Biological Unit for 9C9M: dodecameric; determined by author and by software
Molecular Components in 9C9M
Label Count Molecule
Proteins (8 molecules)
6
Integrase
(Gene symbol: gag-pol)
Molecule annotation
2
Integrase
(Gene symbol: gag-pol)
Molecule annotation
Nucleotides(4 molecules)
2
Viral DNA
Molecule annotation
2
Vdna
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
ZINC IONZINC ION
3
2
(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303