9BYJ: Crystal Structure of Hck in complex with the Src-family kinase inhibitor A-419259

PDB ID: 9BYJDownload
MMDB ID: 253370
PDB Deposition Date: 2024/5/23
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 9BYJ: monomeric; determined by author
Molecular Components in 9BYJ
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase HCK
(Gene symbol: HCK)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
1
7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
2
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
15
THIOCYANATE IONTHIOCYANATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303