9BOQ: Human p97/VCP structure with a triazole inhibitor (NSC799462/dodecamer)

PDB ID: 9BOQDownload
MMDB ID: 251361
PDB Deposition Date: 2024/5/5
Updated in MMDB: 2024/08
Experimental Method:
electron microscopy
Resolution: 3.33  Å
Source Organism:
Similar Structures:
Biological Unit for 9BOQ: dodecameric; determined by author and by software
Molecular Components in 9BOQ
Label Count Molecule
Proteins (12 molecules)
12
Transitional Endoplasmic Reticulum Atpase
(Gene symbol: VCP)
Molecule annotation
Chemicals and Non-standard biopolymers (36 molecules)
1
24
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
12
3-(2,6-difluoro-4-{[(4P)-5-{[(2S)-hexan-2-yl]sulfanyl}-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl (1-methylpiperidin-4-yl)carbamate3-(2,6-difluoro-4-{[(4P)-5-{[(2S)-hexan-2-yl]sulfanyl}-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl (1-methylpiperidin-4-yl)carbamate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303