9BJ1: Crystal structure of inhibitor GNE-6893 bound to HPK1

PDB ID: 9BJ1Download
MMDB ID: 253095
PDB Deposition Date: 2024/4/24
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.18  Å
Source Organism:
Similar Structures:
Biological Unit for 9BJ1: dimeric; determined by author and by software (PISA)
Molecular Components in 9BJ1
Label Count Molecule
Proteins (2 molecules)
2
Mitogen-activated Protein Kinase Kinase Kinase Kinase 1
(Gene symbol: MAP4K1)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
3
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
2
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
3
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
1
SODIUM IONSODIUM ION
6
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303