9B37: Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one concanavalin A dimer. Composite map

PDB ID: 9B37Download
MMDB ID: 247394
PDB Deposition Date: 2024/3/18
Updated in MMDB: 2024/07
Experimental Method:
electron microscopy
Resolution: 6.66  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 9B37: hexameric; determined by author and by software
Molecular Components in 9B37
Label Count Molecule
Proteins (6 molecules)
4
Glutamate Receptor Ionotropic, Kainate 2
Molecule annotation
2
Concanavalin a
Molecule annotation
Chemicals and Non-standard biopolymers (130 molecules)
1
65
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
13
beta-D-mannopyranosebeta-D-mannopyranose
3
14
alpha-D-mannopyranosealpha-D-mannopyranose
4
4
beta-D-galactopyranosebeta-D-galactopyranose
5
4
4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
6
4
GLUTAMIC ACIDGLUTAMIC ACID
7
14
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
8
8
CHOLESTEROLCHOLESTEROL
9
2
ZINC IONZINC ION
10
2
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303