9AXH: Crystal structure of KSR1/MEK1 complex heterotetramer with NST-628

PDB ID: 9AXHDownload
MMDB ID: 245617
PDB Deposition Date: 2024/3/6
Updated in MMDB: 2024/07
Experimental Method:
x-ray diffraction
Resolution: 2.81  Å
Source Organism:
Similar Structures:
Biological Unit for 9AXH: tetrameric; determined by author and by software (PISA)
Molecular Components in 9AXH
Label Count Molecule
Proteins (4 molecules)
2
Dual Specificity Mitogen-activated Protein Kinase Kinase 1
(Gene symbol: MAP2K1)
Molecule annotation
2
Kinase Suppressor of RAS 1
(Gene symbol: KSR1)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
2
Unknown
2
4
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
3
4
MAGNESIUM IONMAGNESIUM ION
4
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303