9AV8: Design and application of synthetic 17B-HSD13 substrates to drug discovery, and to reveal preserved catalytic activity of protective human variants

PDB ID: 9AV8Download
MMDB ID: 255745
PDB Deposition Date: 2024/3/1
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.592  Å
Source Organism:
Similar Structures:
Biological Unit for 9AV8: dimeric; determined by author and by software (PISA)
Molecular Components in 9AV8
Label Count Molecule
Proteins (2 molecules)
2
Hydroxysteroid 17-beta Dehydrogenase 13
(Gene symbol: HSD17B13)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
2
1
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303